STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MGYG_08026Thiamin biosynthesis protein. (508 aa)    
Predicted Functional Partners:
MGYG_02201
Hydroxyethylthiazole kinase.
 
 
 0.994
MGYG_02366
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
    
 0.943
MGYG_05190
NMT1 domain-containing protein.
     
 0.940
MGYG_05687
LMWPc domain-containing protein.
    
  0.910
MGYG_01988
Alkaline phosphatase.
    
 0.906
MGYG_06065
Alkaline phosphatase.
    
 0.906
MGYG_00768
Uncharacterized protein.
 
      0.853
MGYG_06008
Pyridoxal kinase.
   
 
 0.797
MGYG_08741
Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...]
  
  
 0.788
MGYG_04051
Uncharacterized protein.
   
 
 0.757
Your Current Organism:
Nannizzia gypsea
NCBI taxonomy Id: 535722
Other names: Arthroderma gypseum CBS 118893, Microsporum gypseum CBS 118893, N. gypsea CBS 118893, Nannizzia gypsea CBS 118893
Server load: low (22%) [HD]