node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEH84500.1 | AEH84574.1 | Mesop_0002 | Mesop_0077 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310:IPR012309; KEGG: mlo:mll5481 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region. | 0.760 |
AEH84500.1 | AEH88157.1 | Mesop_0002 | Mesop_3715 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: hne:HNE_0563 DNA polymerase III subunit beta; PFAM: DNA polymerase III beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III beta chain; SPTR: DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit. | 0.926 |
AEH84500.1 | AEH88220.1 | Mesop_0002 | Mesop_3779 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310; KEGG: mlo:mlr9524 DNA ligase-like protein; PFAM: ATP dependent DNA ligase; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain. | 0.766 |
AEH84500.1 | AEH88938.1 | Mesop_0002 | Mesop_4515 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: mlo:mll0423 DNA polymerase III subunit delta'; SPTR: DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit. | 0.998 |
AEH84500.1 | polA | Mesop_0002 | Mesop_1753 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
AEH84573.1 | AEH84574.1 | Mesop_0075 | Mesop_0077 | Conserved hypothetical protein; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; KEGG: mlo:mll5484 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily. | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310:IPR012309; KEGG: mlo:mll5481 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region. | 0.938 |
AEH84573.1 | AEH86523.1 | Mesop_0075 | Mesop_2043 | Conserved hypothetical protein; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; KEGG: mlo:mll5484 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily. | COGs: COG3569 Topoisomerase IB; InterPro IPR001631; KEGG: mlo:mll2873 hypothetical protein; PRIAM: DNA topoisomerase; SPTR: Topoisomerase IB-like protein; PFAM: Eukaryotic DNA topoisomerase I, catalytic core. | 0.510 |
AEH84573.1 | AEH88220.1 | Mesop_0075 | Mesop_3779 | Conserved hypothetical protein; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; KEGG: mlo:mll5484 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily. | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310; KEGG: mlo:mlr9524 DNA ligase-like protein; PFAM: ATP dependent DNA ligase; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain. | 0.672 |
AEH84573.1 | AEH90984.1 | Mesop_0075 | Mesop_6663 | Conserved hypothetical protein; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; KEGG: mlo:mll5484 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily. | Metallophosphoesterase; COGs: COG1407 ICC-like phosphoesterase; InterPro IPR004843; KEGG: mlo:mlr5611 hypothetical protein; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase. | 0.793 |
AEH84573.1 | AEH90985.1 | Mesop_0075 | Mesop_6664 | Conserved hypothetical protein; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; KEGG: mlo:mll5484 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily. | DEAD/H associated domain protein; COGs: COG1201 Lhr-like helicase; InterProIPR011545:IPR001650:IPR013701:IPR014021:IPR 014001:IPR017170; KEGG: mlo:mlr5610 ATP dependent DNA helicase; PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: DEAD/H associated domain protein; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase. | 0.802 |
AEH84573.1 | polA | Mesop_0075 | Mesop_1753 | Conserved hypothetical protein; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; KEGG: mlo:mll5484 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.802 |
AEH84574.1 | AEH84500.1 | Mesop_0077 | Mesop_0002 | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310:IPR012309; KEGG: mlo:mll5481 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.760 |
AEH84574.1 | AEH84573.1 | Mesop_0077 | Mesop_0075 | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310:IPR012309; KEGG: mlo:mll5481 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region. | Conserved hypothetical protein; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; KEGG: mlo:mll5484 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily. | 0.938 |
AEH84574.1 | AEH86523.1 | Mesop_0077 | Mesop_2043 | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310:IPR012309; KEGG: mlo:mll5481 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region. | COGs: COG3569 Topoisomerase IB; InterPro IPR001631; KEGG: mlo:mll2873 hypothetical protein; PRIAM: DNA topoisomerase; SPTR: Topoisomerase IB-like protein; PFAM: Eukaryotic DNA topoisomerase I, catalytic core. | 0.611 |
AEH84574.1 | AEH88157.1 | Mesop_0077 | Mesop_3715 | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310:IPR012309; KEGG: mlo:mll5481 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region. | COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: hne:HNE_0563 DNA polymerase III subunit beta; PFAM: DNA polymerase III beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III beta chain; SPTR: DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit. | 0.760 |
AEH84574.1 | AEH88220.1 | Mesop_0077 | Mesop_3779 | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310:IPR012309; KEGG: mlo:mll5481 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region. | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310; KEGG: mlo:mlr9524 DNA ligase-like protein; PFAM: ATP dependent DNA ligase; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain. | 0.717 |
AEH84574.1 | AEH88938.1 | Mesop_0077 | Mesop_4515 | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310:IPR012309; KEGG: mlo:mll5481 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region. | COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: mlo:mll0423 DNA polymerase III subunit delta'; SPTR: DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit. | 0.623 |
AEH84574.1 | AEH90984.1 | Mesop_0077 | Mesop_6663 | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310:IPR012309; KEGG: mlo:mll5481 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region. | Metallophosphoesterase; COGs: COG1407 ICC-like phosphoesterase; InterPro IPR004843; KEGG: mlo:mlr5611 hypothetical protein; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase. | 0.825 |
AEH84574.1 | AEH90985.1 | Mesop_0077 | Mesop_6664 | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310:IPR012309; KEGG: mlo:mll5481 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region. | DEAD/H associated domain protein; COGs: COG1201 Lhr-like helicase; InterProIPR011545:IPR001650:IPR013701:IPR014021:IPR 014001:IPR017170; KEGG: mlo:mlr5610 ATP dependent DNA helicase; PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: DEAD/H associated domain protein; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase. | 0.801 |
AEH84574.1 | ligA | Mesop_0077 | Mesop_3551 | COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059:IPR012310:IPR012309; KEGG: mlo:mll5481 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.913 |