STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH84897.1Protein of unknown function UPF0079; COGs: COG3178 phosphotransferase related to Ser/Thr protein kinase; InterPro IPR003442:IPR002575:IPR012180; KEGG: mlo:mll5086 hypothetical protein; PFAM: protein of unknown function UPF0079; aminoglycoside phosphotransferase; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised P-loop hydrolase UPF0079; Phosphotransferase enzyme family; TIGRFAM: ATPase, YjeE family. (503 aa)    
Predicted Functional Partners:
AEH84898.1
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: mlo:mll5085 hypothetical protein; PFAM: Nucleotidyl transferase; SPTR: Nucleotidyl transferase; PFAM: Nucleotidyl transferase.
 
 
 0.989
AEH84534.1
Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905:IPR017861; KEGG: mlo:mlr5530 hypothetical protein; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22 glycoprotease; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ.
 
 
 0.980
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
    
 0.940
AEH88387.1
Glycoside hydrolase family 3 domain protein; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: mlo:mll9166 glycosy hydrolase family protein; PFAM: glycoside hydrolase family 3 domain protein; SPTR: Beta-N-acetylhexosaminidase; PFAM: Glycosyl hydrolase family 3 N terminal domain.
    
 0.926
AEH88417.1
Glycoside hydrolase family 3 domain protein; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764:IPR019800; KEGG: mlo:mll1089 sugar hydrolase; PFAM: glycoside hydrolase family 3 domain protein; SPTR: Beta-N-acetylhexosaminidase; PFAM: Glycosyl hydrolase family 3 N terminal domain.
    
 0.926
tsaD
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
 
 0.914
AEH84896.1
PAS/PAC sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR005467:IPR003661:IPR003594:IPR004358:IPR 000014; KEGG: mlo:mll5087 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
     0.909
AEH84900.1
Double-strand break repair helicase AddA; COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR014016:IPR014017:IPR000212:IPR014151; KEGG: mlo:mll5083 ATP-dependent nuclease subunit A; PFAM: UvrD/REP helicase; SPTR: Double-strand break repair helicase AddA; TIGRFAM: double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; TIGRFAM: double-strand break repair helicase AddA, alphaproteobacterial type; Belongs to the helicase family. UvrD subfamily.
 
   
 0.879
AEH84899.1
Double-strand break repair protein AddB; COGs: COG3893 Inactivated superfamily I helicase; InterPro IPR014153; KEGG: mlo:mll5084 hypothetical protein; SPTR: Double-strand break repair protein AddB; TIGRFAM: double-strand break repair protein AddB; TIGRFAM: double-strand break repair protein AddB, alphaproteobacterial type.
 
     0.851
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
 
 0.810
Your Current Organism:
Mesorhizobium opportunistum
NCBI taxonomy Id: 536019
Other names: M. opportunistum WSM2075, Mesorhizobium opportunistum WSM2075, Mesorhizobium opportunistum str. WSM2075, Mesorhizobium opportunistum strain WSM2075, Mesorhizobium sp. LMG 24607, Mesorhizobium sp. WSM2075
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