STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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[Homology]
Score
AEH85245.1Diguanylate cyclase/phosphodiesterase; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR001633:IPR000160; KEGG: mlo:mlr4740 hypothetical protein; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (449 aa)    
Predicted Functional Partners:
AEH87092.1
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: mlo:mlr8123 hypothetical protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.802
AEH86104.1
Diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterProIPR000014:IPR000700:IPR000160:IPR001610:IPR 013655:IPR013767; KEGG: mlo:mll3491 hypothetical protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
 
0.731
AEH87769.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000700:IPR001633:IPR000160:IPR 001610:IPR013655:IPR000408; KEGG: mlo:mll1848 hypothetical protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: PA [...]
 
 
0.706
AEH90004.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and periplasmic/7TM domain sensor(s); COGs: COG2200 FOG: EAL domain; InterProIPR011622:IPR011623:IPR013655:IPR000160:IPR 001633:IPR000700:IPR001610:IPR000014; KEGG: mes:Meso_0757 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; Diverse 7TM receptor transmembrane region; Diverse 7TM receptor extracellular region 2; PAS fold-3 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; SPTR: Diguanylate cyclase/phosphodi [...]
 
 
0.638
AEH85871.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR003661:IPR003594:IPR 004358; KEGG: mlo:mlr3786 hybrid sensory histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 0.601
AEH86935.1
Diguanylate cyclase/phosphodiesterase; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160:IPR001633; KEGG: mlo:mll2297 hypothetical protein; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
0.557
AEH87588.1
Diguanylate cyclase with PAS/PAC sensor; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterProIPR000700:IPR000160:IPR000014:IPR011620:IPR 013656; KEGG: avi:Avi_0610 two component response regulator; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: 5TMR of 5TMR-LYT; GGDEF domain; PAS fold; TIGRFA [...]
 
0.527
AEH90887.1
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterProIPR000014:IPR002052:IPR000780:IPR000673:IPR 013656:IPR011102:IPR000700; KEGG: bid:Bind_0707 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; PFAM: HWE histidine kinase; CheB methylesterase; MCP methyltransferase CheR-type; PAS fold-4 domain protein; SMART: MCP methyltransferase CheR-type; SPTR: MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; CheR methy [...]
 
  
 0.521
AEH85941.1
COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003018:IPR013655:IPR011102; KEGG: mlo:mlr3690 hypothetical protein; PFAM: HWE histidine kinase; GAF domain protein; PAS fold-3 domain protein; SPTR: Signal transduction histidine kinase; PFAM: GAF domain; HWE histidine kinase.
 
 
 0.497
AEH85244.1
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347:IPR002198; KEGG: mlo:mlr4741 short chain dehydrogenase/reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
       0.488
Your Current Organism:
Mesorhizobium opportunistum
NCBI taxonomy Id: 536019
Other names: M. opportunistum WSM2075, Mesorhizobium opportunistum WSM2075, Mesorhizobium opportunistum str. WSM2075, Mesorhizobium opportunistum strain WSM2075, Mesorhizobium sp. LMG 24607, Mesorhizobium sp. WSM2075
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