STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH86186.1D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: mlo:mlr3367 phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (328 aa)    
Predicted Functional Partners:
AEH85812.1
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
 
 0.972
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
  
 0.916
AEH86187.1
GntR domain protein; COGs: COG2186 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: mlo:mlr3366 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR domain protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
       0.789
AEH86188.1
Mandelate racemase/muconate lactonizing protein; COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR018110:IPR013341:IPR013342; KEGG: mlo:mlr3365 hypothetical protein; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: Mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain.
       0.789
AEH86185.1
KEGG: mlo:mlr3368 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.653
AEH86189.1
Xylose isomerase domain protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: mlo:mlr3364 D-tagatose 3-epimerase; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel.
       0.608
AEH90712.1
COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterPro IPR000873:IPR003679:IPR020845; KEGG: mlo:mlr6282 phosphinothricin tripeptide synthetase B; PFAM: AMP-dependent synthetase and ligase; aminoglycoside 3-N-acetyltransferase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; Aminoglycoside 3-N-acetyltransferase; TIGRFAM: amino acid adenylation domain.
  
 
 0.579
AEH88691.1
Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
     0.522
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
   0.487
AEH87286.1
Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG0498 Threonine synthase; InterPro IPR001926; KEGG: mlo:mll9542 threonine synthase-like protein; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase.
 
  
 0.449
Your Current Organism:
Mesorhizobium opportunistum
NCBI taxonomy Id: 536019
Other names: M. opportunistum WSM2075, Mesorhizobium opportunistum WSM2075, Mesorhizobium opportunistum str. WSM2075, Mesorhizobium opportunistum strain WSM2075, Mesorhizobium sp. LMG 24607, Mesorhizobium sp. WSM2075
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