STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH86962.1Integrase family protein; InterPro IPR002104; KEGG: bmr:BMI_I1486 site-specific recombinase, phage integrase family; PFAM: integrase family protein; SPTR: Integrase family protein; PFAM: Phage integrase family. (396 aa)    
Predicted Functional Partners:
AEH86132.1
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: mlo:mll3453 hypothetical protein; PFAM: phosphoribosyltransferase; SPTR: Putative uncharacterized protein; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
  
    0.597
AEH90712.1
COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterPro IPR000873:IPR003679:IPR020845; KEGG: mlo:mlr6282 phosphinothricin tripeptide synthetase B; PFAM: AMP-dependent synthetase and ligase; aminoglycoside 3-N-acetyltransferase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; Aminoglycoside 3-N-acetyltransferase; TIGRFAM: amino acid adenylation domain.
 
 
 0.583
AEH90929.1
Multi-sensor hybrid histidine kinase; COGs: COG0591 Na+/proline symporter; InterProIPR004358:IPR013656:IPR003661:IPR003594:IPR 001789:IPR005467:IPR001734; KEGG: mlo:mll5691 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kin [...]
  
  
 0.494
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.485
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
   
    0.485
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.474
AEH86963.1
KEGG: nwi:Nwi_0274 hypothetical protein; SPTR: Putative uncharacterized protein.
     
 0.472
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.446
AEH86961.1
Protein of unknown function DUF541; COGs: COG2968 conserved hypothetical protein; InterPro IPR007497; KEGG: mlo:mlr2408 hypothetical protein; PFAM: protein of unknown function DUF541; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF541).
       0.415
Your Current Organism:
Mesorhizobium opportunistum
NCBI taxonomy Id: 536019
Other names: M. opportunistum WSM2075, Mesorhizobium opportunistum WSM2075, Mesorhizobium opportunistum str. WSM2075, Mesorhizobium opportunistum strain WSM2075, Mesorhizobium sp. LMG 24607, Mesorhizobium sp. WSM2075
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.