STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C3MJH7Actin 1. (375 aa)    
Predicted Functional Partners:
A0A5C3MPJ1
Nonmuscle myosin heavy chain b; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.957
A0A5C3NQT9
Actin-related protein Arp4p; Belongs to the actin family.
  
 
0.956
A0A5C3NAW7
Uncharacterized protein.
    
 0.954
A0A5C3N1L1
Actin-domain-containing protein; Belongs to the actin family.
    
0.949
A0A5C3MM52
Actin-like protein Arp3; Belongs to the actin family.
   
0.945
A0A5C3MXK7
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
  
 
0.945
A0A5C3N3A3
Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family.
    
 0.943
A0A5C3N329
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
    
 0.936
A0A5C3N091
WH1-domain-containing protein.
    
 0.931
A0A5C3MWP2
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.930
Your Current Organism:
Heliocybe sulcata
NCBI taxonomy Id: 5364
Other names: H. sulcata, Lentinus sulcatus
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