STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C3MSV5Phospholipase D/nuclease. (602 aa)    
Predicted Functional Partners:
A0A5C3NAY9
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
    
 
 0.927
A0A5C3N6G6
P-loop containing nucleoside triphosphate hydrolase protein.
    
 
 0.816
A0A5C3MRF5
ERCC4 domain-containing protein.
   
 
 0.797
A0A5C3MYQ8
Ku70-like protein.
     
 0.794
A0A5C3MR79
SPOC domain-like protein.
    
 0.792
A0A5C3N208
DNA ligase.
   
 
 0.678
A0A5C3MWN4
POLXc domain-containing protein.
    
 
 0.669
A0A5C3N5L9
POLXc domain-containing protein.
    
 
 0.669
A0A5C3MUJ0
HRDC domain-containing protein.
     
 0.654
A0A5C3NE61
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
     
 0.654
Your Current Organism:
Heliocybe sulcata
NCBI taxonomy Id: 5364
Other names: H. sulcata, Lentinus sulcatus
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