STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C3MTI1Peptide hydrolase; Belongs to the peptidase M28 family. (849 aa)    
Predicted Functional Partners:
A0A5C3MQH7
UBA domain-containing protein.
    
 0.600
A0A5C3MW41
Alpha/beta-hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
  0.508
A0A5C3MPD7
Clathrin adaptor, mu subunit; Belongs to the adaptor complexes medium subunit family.
     
 0.503
A0A5C3MRS9
AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
    
 0.476
A0A5C3NAT5
AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
    
 0.476
A0A5C3N1L3
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
  0.461
A0A5C3NCJ2
V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.
   
 
 0.457
A0A5C3MQM9
P-loop containing nucleoside triphosphate hydrolase protein.
 
      0.454
A0A5C3MSS7
CYTOSOL_AP domain-containing protein.
     
 0.452
A0A5C3MR25
ATPase V1/A1 complex subunit E.
     
 0.442
Your Current Organism:
Heliocybe sulcata
NCBI taxonomy Id: 5364
Other names: H. sulcata, Lentinus sulcatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.