node1 | node2 | node1 annotation | node2 annotation | score |
A0A5C3MND5 | A0A5C3MPE9 | Single hybrid motif-containing protein. | Dihydrolipoyl dehydrogenase. | 0.995 |
A0A5C3MND5 | A0A5C3MTC6 | Single hybrid motif-containing protein. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.773 |
A0A5C3MND5 | A0A5C3MV23 | Single hybrid motif-containing protein. | Oxoglutarate dehydrogenase. | 0.962 |
A0A5C3MND5 | A0A5C3MXR9 | Single hybrid motif-containing protein. | Dihydrolipoamide succinyltransferase. | 0.942 |
A0A5C3MND5 | A0A5C3N2D4 | Single hybrid motif-containing protein. | Isochorismatase hydrolase. | 0.903 |
A0A5C3MND5 | A0A5C3NDH6 | Single hybrid motif-containing protein. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.662 |
A0A5C3MND5 | A0A5C3NGI3 | Single hybrid motif-containing protein. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.944 |
A0A5C3MND5 | A0A5C3NHE2 | Single hybrid motif-containing protein. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.719 |
A0A5C3MND5 | A0A5C3NID8 | Single hybrid motif-containing protein. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.968 |
A0A5C3MND5 | A0A5C3NUP3 | Single hybrid motif-containing protein. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.939 |
A0A5C3MPE9 | A0A5C3MND5 | Dihydrolipoyl dehydrogenase. | Single hybrid motif-containing protein. | 0.995 |
A0A5C3MPE9 | A0A5C3MTC6 | Dihydrolipoyl dehydrogenase. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.995 |
A0A5C3MPE9 | A0A5C3MV23 | Dihydrolipoyl dehydrogenase. | Oxoglutarate dehydrogenase. | 0.994 |
A0A5C3MPE9 | A0A5C3MXR9 | Dihydrolipoyl dehydrogenase. | Dihydrolipoamide succinyltransferase. | 0.998 |
A0A5C3MPE9 | A0A5C3N2D4 | Dihydrolipoyl dehydrogenase. | Isochorismatase hydrolase. | 0.995 |
A0A5C3MPE9 | A0A5C3NDH6 | Dihydrolipoyl dehydrogenase. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.797 |
A0A5C3MPE9 | A0A5C3NGI3 | Dihydrolipoyl dehydrogenase. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.897 |
A0A5C3MPE9 | A0A5C3NHE2 | Dihydrolipoyl dehydrogenase. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.744 |
A0A5C3MPE9 | A0A5C3NID8 | Dihydrolipoyl dehydrogenase. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
A0A5C3MPE9 | A0A5C3NUP3 | Dihydrolipoyl dehydrogenase. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.975 |