STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C3MVG4Histone H2A; Belongs to the histone H2A family. (139 aa)    
Predicted Functional Partners:
A0A5C3NDG3
Histone H2B; Belongs to the histone H2B family.
 
 0.970
A0A5C3MUF3
Histone H2B; Belongs to the histone H2B family.
 
 0.957
A0A5C3N7K6
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.934
A0A5C3NIT3
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.934
A0A5C3N2Z6
F-box domain-containing protein.
   
 0.889
A0A5C3MP84
Histone H2A; Belongs to the histone H2A family.
  
0.881
A0A5C3MWK8
Ubiquitin-40S ribosomal protein S31 fusion protein.
   
  0.876
A0A5C3NSH1
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.852
A0A5C3NEV3
Histone H3; Belongs to the histone H3 family.
 
 
 0.846
A0A5C3N593
Histone H3; Belongs to the histone H3 family.
 
 
 0.845
Your Current Organism:
Heliocybe sulcata
NCBI taxonomy Id: 5364
Other names: H. sulcata, Lentinus sulcatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.