STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C3N2C0RING-type domain-containing protein. (742 aa)    
Predicted Functional Partners:
A0A5C3NAN5
Ubiquitin-conjugating enzyme 9; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.813
A0A5C3N0R7
Ubiquitin-like protein.
    
 0.728
A0A5C3N1M3
Ubiquitin-like protein.
    
 0.728
A0A5C3N2J9
Ubiquitin-like protein.
    
 0.728
A0A5C3NKF8
Uncharacterized protein.
    
 0.724
A0A5C3NAY9
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
   
 
 0.599
A0A5C3MZ33
Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.581
A0A5C3MQ20
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.567
A0A5C3MZR5
Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.559
A0A5C3NEA1
Uncharacterized protein.
    
 0.559
Your Current Organism:
Heliocybe sulcata
NCBI taxonomy Id: 5364
Other names: H. sulcata, Lentinus sulcatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.