STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C3N3C2HECT domain-containing protein. (1938 aa)    
Predicted Functional Partners:
A0A5C3MST7
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.999
A0A5C3MQ20
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.995
A0A5C3MZ33
Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.995
A0A5C3MZR5
Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.995
A0A5C3NEA1
Uncharacterized protein.
   
 0.995
A0A5C3NGP1
UBC-like protein.
   
 0.995
A0A5C3NHW4
Uncharacterized protein.
   
 0.995
A0A5C3N9I3
U-box domain-containing protein.
   
 0.994
A0A5C3NIH2
Ubiquitin activating enzyme.
   
 0.989
A0A5C3NN77
E2_bind domain-containing protein.
    
 0.989
Your Current Organism:
Heliocybe sulcata
NCBI taxonomy Id: 5364
Other names: H. sulcata, Lentinus sulcatus
Server load: low (16%) [HD]