STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C3NQ78Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family. (236 aa)    
Predicted Functional Partners:
A0A5C3N8V0
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
 
 
   0.967
A0A5C3MTN1
ARM repeat-containing protein.
    
   0.949
A0A5C3NLL4
Importin subunit alpha; Belongs to the importin alpha family.
    
   0.949
A0A5C3MKH3
Brix-domain-containing protein.
   
   0.915
A0A5C3MKM4
ARM repeat-containing protein.
   
 
 0.899
A0A5C3N0F9
Uncharacterized protein.
   
   0.894
A0A5C3N4H8
Ebp2-domain-containing protein.
   
   0.883
A0A5C3NE04
Ribosome biogenesis protein BRX1.
   
   0.881
A0A5C3NGI4
20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.
   
  
 0.881
A0A5C3NJS4
Nop52-domain-containing protein.
   
 
 0.881
Your Current Organism:
Heliocybe sulcata
NCBI taxonomy Id: 5364
Other names: H. sulcata, Lentinus sulcatus
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