Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nadENAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (641 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.946
nadK
NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.942
cobB-2
Transcriptional regulator, Sir2 family; KEGG: pgi:PG0004 2.6e-78 NAD-dependent deacetylase K01463; Psort location: Cytoplasmic, score: 8.96; Belongs to the sirtuin family. Class III subfamily.
    
 0.940
EEC94392.1
Hydrolase, NUDIX family; KEGG: bfs:BF1422 1.1e-84 putative NADH pyrophosphatase K03659.
  
 
 0.907
cutC
CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family.
   
   0.754
EEC96567.1
Hypothetical protein.
       0.736
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.626
guaA-2
GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 5.5e-218 putative GMP synthase [glutamine-hydrolyzing] K01951; Psort location: Cytoplasmic, score: 8.96.
     
 0.626
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.624
purL
Putative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
     
 0.596
Your Current Organism:
Parabacteroides johnsonii
NCBI taxonomy Id: 537006
Other names: P. johnsonii DSM 18315, Parabacteroides johnsonii DSM 18315, Parabacteroides johnsonii JCM 13406, Parabacteroides johnsonii M-165, Parabacteroides johnsonii str. DSM 18315, Parabacteroides johnsonii strain DSM 18315
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