STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaNDNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (374 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 0.999
holA
KEGG: bfr:BF2396 7.6e-102 DNA polymerase III delta subunit K02340.
 
 
 0.997
EEC94415.1
KEGG: bfr:BF0712 0. DNA polymerase III alpha subunit K02337; Psort location: Cytoplasmic, score: 9.26.
  
 
 0.996
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 0.993
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.990
EEC97881.1
Hypothetical protein; KEGG: cal:orf19.6291 4.5e-05 FUN30; helicase of the Snf2/Rad54 family K01509.
  
 0.989
EEC96413.1
KEGG: bth:BT1363 8.5e-103 DNA polymerase III epsilon subunit K02342; Psort location: Cytoplasmic, score: 8.96.
  
 0.987
EEC96552.1
Hypothetical protein; KEGG: bth:BT3820 3.2e-119 putative DNA polymerase III, delta subunit K02341; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.986
dinB
ImpB/MucB/SamB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
   
 0.981
EEC94909.1
ImpB/MucB/SamB family protein; KEGG: btl:BALH_p0040 3.4e-44 uvrX; DNA-damage repair protein (DNA polymerase IV) K00961; Psort location: Cytoplasmic, score: 8.96.
   
 0.981
Your Current Organism:
Parabacteroides johnsonii
NCBI taxonomy Id: 537006
Other names: P. johnsonii DSM 18315, Parabacteroides johnsonii DSM 18315, Parabacteroides johnsonii JCM 13406, Parabacteroides johnsonii M-165, Parabacteroides johnsonii str. DSM 18315, Parabacteroides johnsonii strain DSM 18315
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.