STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (353 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.998
EEC96201.1
KEGG: bfs:BF3266 1.5e-146 leuC; putative 3-isopropylmalate dehydratase large subunit K01703; Psort location: Cytoplasmic, score: 9.26.
 0.997
EEC96202.1
KEGG: bfs:BF3266 4.4e-67 leuC; putative 3-isopropylmalate dehydratase large subunit K01703.
 
 0.984
ilvN
KEGG: bth:BT2076 4.7e-47 acetohydroxyacid synthase small subunit K01653; Psort location: Cytoplasmic, score: 8.96.
 
 0.978
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 0.976
EEC96198.1
HMGL-like protein; KEGG: bfr:BF3445 1.2e-192 leuA; 2-isopropylmalate synthase LeuA K01649; Psort location: Cytoplasmic, score: 8.96; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.964
ilvB
Acetolactate synthase, large subunit, biosynthetic type; KEGG: bth:BT2077 5.0e-201 acetolactate synthase large subunit K01652; Psort location: Cytoplasmic, score: 8.96.
 
 0.962
ilvC
KEGG: bfs:BF3546 6.9e-156 putative reductoisomerase K00053.
 
  
 0.935
ilvD
KEGG: bfr:BF3763 2.8e-271 dihydroxy-acid dehydratase K01687; Psort location: Cytoplasmic, score: 8.96; Belongs to the IlvD/Edd family.
 
  
 0.924
EEC96583.1
Glutamate synthase central domain protein; KEGG: bth:BT0553 0. glutamate synthase, large subunit K00265; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.921
Your Current Organism:
Parabacteroides johnsonii
NCBI taxonomy Id: 537006
Other names: P. johnsonii DSM 18315, Parabacteroides johnsonii DSM 18315, Parabacteroides johnsonii JCM 13406, Parabacteroides johnsonii M-165, Parabacteroides johnsonii str. DSM 18315, Parabacteroides johnsonii strain DSM 18315
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.