STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (357 aa)    
Predicted Functional Partners:
aroA
Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 
 0.994
EEC97441.1
Putative 3-deoxy-7-phosphoheptulonate synthase; KEGG: bth:BT3934 5.6e-154 phospho-2-dehydro-3-deoxyheptonate aldolase / chorismate mutase K04516:K03856; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.993
nifJ
KEGG: bth:BT1747 0. pyruvate-flavodoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 8.96.
   
 
 0.981
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
  
 0.972
EEC96641.1
KEGG: bth:BT4215 3.5e-90 shikimate 5-dehydrogenase K00014.
 
 0.969
EEC97827.1
2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: pgi:PG0429 7.6e-237 pyruvate synthase K00174.
   
 
 0.941
EEC97440.1
KEGG: bth:BT3933 3.3e-94 tyrA; prephenate dehydrogenase / chorismate mutase K00210:K01850.
  
 0.910
EEC97635.1
Glutamine amidotransferase, class I; KEGG: bth:BT0531 2.0e-69 anthranilate synthase component II K01658; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.904
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 
 0.872
EEC97636.1
Chorismate binding enzyme; KEGG: bfs:BF2673 9.8e-189 trpE; anthranilate synthase component I K01657; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.867
Your Current Organism:
Parabacteroides johnsonii
NCBI taxonomy Id: 537006
Other names: P. johnsonii DSM 18315, Parabacteroides johnsonii DSM 18315, Parabacteroides johnsonii JCM 13406, Parabacteroides johnsonii M-165, Parabacteroides johnsonii str. DSM 18315, Parabacteroides johnsonii strain DSM 18315
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