STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recQ-2KEGG: bfr:BF4076 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 8.96. (729 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.907
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 0.854
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.842
EEC95968.1
KEGG: eci:UTI89_C0417 1.8e-102 sbcC; exonuclease SbcC K03546; Psort location: Extracellular, score: 8.89.
  
 0.808
mutL
DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
 0.807
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
     
 0.771
EEC96382.1
UvrD/REP helicase; KEGG: bfs:BF2555 2.1e-83 putative helicase K03657.
  
 0.714
EEC96355.1
UvrD/REP helicase; KEGG: bfr:BF2526 1.7e-159 ATP-dependent DNA helicase K03657.
  
 0.714
EEC95160.1
UvrD/REP helicase; KEGG: pha:PSHAa1096 2.7e-51 uvrD; DNA helicase II K01529; Psort location: Cytoplasmic, score: 8.96.
  
 0.714
EEC94191.1
KEGG: bth:BT0105 5.3e-94 DNA topoisomerase I (Omega-protein) K03169.
 
 
 0.704
Your Current Organism:
Parabacteroides johnsonii
NCBI taxonomy Id: 537006
Other names: P. johnsonii DSM 18315, Parabacteroides johnsonii DSM 18315, Parabacteroides johnsonii JCM 13406, Parabacteroides johnsonii M-165, Parabacteroides johnsonii str. DSM 18315, Parabacteroides johnsonii strain DSM 18315
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