| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEC95183.1 | EEC95184.1 | PRABACTJOHN_03437 | PRABACTJOHN_03438 | Outer membrane protein transport protein, Ompp1/FadL/TodX family; Psort location: OuterMembrane, score: 10.00. | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.434 |
| EEC95184.1 | EEC95183.1 | PRABACTJOHN_03438 | PRABACTJOHN_03437 | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Outer membrane protein transport protein, Ompp1/FadL/TodX family; Psort location: OuterMembrane, score: 10.00. | 0.434 |
| EEC95184.1 | EEC97474.1 | PRABACTJOHN_03438 | PRABACTJOHN_01120 | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative queuosine biosynthesis protein QueD; KEGG: bfs:BF3400 2.6e-46 putative 6-pyruvoyl tetrahydropterin synthase K01737; Psort location: Cytoplasmic, score: 8.96. | 0.939 |
| EEC95184.1 | EEC98411.1 | PRABACTJOHN_03438 | PRABACTJOHN_00164 | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Transcriptional regulator, MerR family; KEGG: eci:UTI89_C3737 1.6e-05 yhdM; Zn(II)-responsive regulator of ZntA; Psort location: Cytoplasmic, score: 8.96. | 0.558 |
| EEC95184.1 | murD | PRABACTJOHN_03438 | PRABACTJOHN_00231 | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.560 |
| EEC95184.1 | nrdG | PRABACTJOHN_03438 | PRABACTJOHN_04327 | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.768 |
| EEC95184.1 | queE | PRABACTJOHN_03438 | PRABACTJOHN_01119 | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.968 |
| EEC95184.1 | queF | PRABACTJOHN_03438 | PRABACTJOHN_03440 | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | preQ(1) synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.963 |
| EEC97474.1 | EEC95184.1 | PRABACTJOHN_01120 | PRABACTJOHN_03438 | Putative queuosine biosynthesis protein QueD; KEGG: bfs:BF3400 2.6e-46 putative 6-pyruvoyl tetrahydropterin synthase K01737; Psort location: Cytoplasmic, score: 8.96. | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.939 |
| EEC97474.1 | nrdG | PRABACTJOHN_01120 | PRABACTJOHN_04327 | Putative queuosine biosynthesis protein QueD; KEGG: bfs:BF3400 2.6e-46 putative 6-pyruvoyl tetrahydropterin synthase K01737; Psort location: Cytoplasmic, score: 8.96. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.866 |
| EEC97474.1 | queE | PRABACTJOHN_01120 | PRABACTJOHN_01119 | Putative queuosine biosynthesis protein QueD; KEGG: bfs:BF3400 2.6e-46 putative 6-pyruvoyl tetrahydropterin synthase K01737; Psort location: Cytoplasmic, score: 8.96. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.996 |
| EEC97474.1 | queF | PRABACTJOHN_01120 | PRABACTJOHN_03440 | Putative queuosine biosynthesis protein QueD; KEGG: bfs:BF3400 2.6e-46 putative 6-pyruvoyl tetrahydropterin synthase K01737; Psort location: Cytoplasmic, score: 8.96. | preQ(1) synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.910 |
| EEC98411.1 | EEC95184.1 | PRABACTJOHN_00164 | PRABACTJOHN_03438 | Transcriptional regulator, MerR family; KEGG: eci:UTI89_C3737 1.6e-05 yhdM; Zn(II)-responsive regulator of ZntA; Psort location: Cytoplasmic, score: 8.96. | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.558 |
| murD | EEC95184.1 | PRABACTJOHN_00231 | PRABACTJOHN_03438 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.560 |
| nrdG | EEC95184.1 | PRABACTJOHN_04327 | PRABACTJOHN_03438 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.768 |
| nrdG | EEC97474.1 | PRABACTJOHN_04327 | PRABACTJOHN_01120 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Putative queuosine biosynthesis protein QueD; KEGG: bfs:BF3400 2.6e-46 putative 6-pyruvoyl tetrahydropterin synthase K01737; Psort location: Cytoplasmic, score: 8.96. | 0.866 |
| nrdG | queF | PRABACTJOHN_04327 | PRABACTJOHN_03440 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | preQ(1) synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.746 |
| queE | EEC95184.1 | PRABACTJOHN_01119 | PRABACTJOHN_03438 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.968 |
| queE | EEC97474.1 | PRABACTJOHN_01119 | PRABACTJOHN_01120 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Putative queuosine biosynthesis protein QueD; KEGG: bfs:BF3400 2.6e-46 putative 6-pyruvoyl tetrahydropterin synthase K01737; Psort location: Cytoplasmic, score: 8.96. | 0.996 |
| queE | queF | PRABACTJOHN_01119 | PRABACTJOHN_03440 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | preQ(1) synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.877 |