Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrFKEGG: bfr:BF0909 1.6e-115 orotidine 5'-phosphate decarboxylase K01591; Belongs to the OMP decarboxylase family. Type 2 subfamily. (280 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.991
EEC97506.1
KEGG: bth:BT2791 1.2e-85 uracil phosphoribosyltransferase K00761.
  
 
 0.930
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.926
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.920
EEC98099.1
Phosphoribulokinase/uridine kinase family protein; KEGG: bfs:BF4152 5.8e-175 putative phosphoribulose/uridine kinase K01868; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.910
EEC95126.1
Hypothetical protein; KEGG: bfr:BF0911 7.4e-191 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.910
EEC97472.1
Amidohydrolase family protein; KEGG: pgi:PG0919 3.2e-151 pyrC; dihydroorotase K01465; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.908
maf
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     
  0.900
carA
Carbamoyl-phosphate synthase, small subunit; KEGG: bth:BT0556 1.7e-161 carbamoyl phosphate synthetase III (glutamine-hydrolyzing) K01956; Psort location: Cytoplasmic, score: 8.96; Belongs to the CarA family.
  
  
 0.889
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
  
    0.850
Your Current Organism:
Parabacteroides johnsonii
NCBI taxonomy Id: 537006
Other names: P. johnsonii DSM 18315, Parabacteroides johnsonii DSM 18315, Parabacteroides johnsonii JCM 13406, Parabacteroides johnsonii M-165, Parabacteroides johnsonii str. DSM 18315, Parabacteroides johnsonii strain DSM 18315
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