STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrFKEGG: bfr:BF0909 1.6e-115 orotidine 5'-phosphate decarboxylase K01591; Belongs to the OMP decarboxylase family. Type 2 subfamily. (280 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.989
EEC97472.1
Amidohydrolase family protein; KEGG: pgi:PG0919 3.2e-151 pyrC; dihydroorotase K01465; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.926
carA
Carbamoyl-phosphate synthase, small subunit; KEGG: bth:BT0556 1.7e-161 carbamoyl phosphate synthetase III (glutamine-hydrolyzing) K01956; Psort location: Cytoplasmic, score: 8.96; Belongs to the CarA family.
  
  
 0.922
EEC95126.1
Hypothetical protein; KEGG: bfr:BF0911 7.4e-191 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.893
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
  
 
  0.876
pyrD
Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.876
EEC95808.1
Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.876
pyrK
Oxidoreductase NAD-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
  
 
 0.866
EEC94588.1
Oxidoreductase NAD-binding domain protein; KEGG: bth:BT4310 4.6e-111 NADPH-dependent glutamate synthase small chain K00266; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.866
EEC97506.1
KEGG: bth:BT2791 1.2e-85 uracil phosphoribosyltransferase K00761.
  
 
 0.825
Your Current Organism:
Parabacteroides johnsonii
NCBI taxonomy Id: 537006
Other names: P. johnsonii DSM 18315, Parabacteroides johnsonii DSM 18315, Parabacteroides johnsonii JCM 13406, Parabacteroides johnsonii M-165, Parabacteroides johnsonii str. DSM 18315, Parabacteroides johnsonii strain DSM 18315
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