Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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accCacetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (528 aa)    
Predicted Functional Partners:
EEC94314.1
Biotin-requiring enzyme; KEGG: pfu:PF0673 1.8e-13 methylmalonyl-CoA decarboxylase gamma chain K01606.
 
  
  0.982
fabD
[acyl-carrier-protein] S-malonyltransferase; KEGG: pgi:PG0138 2.5e-119 fabD; malonyl CoA-acyl carrier protein transacylase K00645.
 
 
 0.977
EEC96205.1
KEGG: bar:GBAA1826 8.0e-75 3-oxoacyl-(acyl-carrier-protein) synthase III, putative K00648; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.969
fabHA
Beta-ketoacyl-acyl-carrier-protein synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.966
fabHA-2
KEGG: bth:BT3834 4.8e-29 3-oxoacyl-[acyl-carrier-protein] synthase III K00648.
 
 
 0.964
EEC94270.1
Biotin-requiring enzyme; KEGG: bth:BT1697 7.6e-281 pyruvate carboxylase subunit B K01960.
 
 0.960
EEC97329.1
HMGL-like protein; KEGG: efa:EF3317 2.5e-71 carboxylase, putative K01571; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.955
EEC94313.1
Carboxyl transferase domain protein; KEGG: bfr:BF3531 6.6e-222 propionyl-CoA carboxylase beta chain K01966; Psort location: Cytoplasmic, score: 8.96.
 
 0.950
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.937
nifJ
KEGG: bth:BT1747 0. pyruvate-flavodoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 8.96.
  
 0.934
Your Current Organism:
Parabacteroides johnsonii
NCBI taxonomy Id: 537006
Other names: P. johnsonii DSM 18315, Parabacteroides johnsonii DSM 18315, Parabacteroides johnsonii JCM 13406, Parabacteroides johnsonii M-165, Parabacteroides johnsonii str. DSM 18315, Parabacteroides johnsonii strain DSM 18315
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