STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (399 aa)    
Predicted Functional Partners:
trpC
KEGG: bth:BT0529 6.2e-68 indole-3-glycerol phosphate synthase K01609; Psort location: Cytoplasmic, score: 8.96; Belongs to the TrpC family.
 
 0.999
trpF
KEGG: bfr:BF2655 1.2e-48 putative N-(5'-phosphoribosyl)anthranilate isomerase K01817; Psort location: Cytoplasmic, score: 8.96; Belongs to the TrpF family.
 
 0.999
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.995
EFB36949.1
Glutamine amidotransferase, class I; KEGG: bth:BT0531 1.6e-69 anthranilate synthase component II K01658; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.992
EFB36948.1
Chorismate binding enzyme; KEGG: bfs:BF2673 1.3e-168 trpE; anthranilate synthase component I K01657; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.944
ilvA
KEGG: tma:TM0356 4.4e-106 threonine dehydratase catabolic K01754; Psort location: Cytoplasmic, score: 8.96.
  
 0.859
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.858
EFB34481.1
KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase.
  
 
 0.841
EFB36119.1
Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 
0.839
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
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