node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFB34749.1 | EFB35735.1 | PREVCOP_05729 | PREVCOP_04639 | Hypothetical protein. | DnaJ domain protein. | 0.893 |
EFB34749.1 | EFB36483.1 | PREVCOP_05729 | PREVCOP_03861 | Hypothetical protein. | DnaJ domain protein; KEGG: cme:CMJ043C 4.4e-07 phycocyanobilin lyase alpha subunit K02288; Psort location: Cytoplasmic, score: 9.26. | 0.875 |
EFB34749.1 | EFB36548.1 | PREVCOP_05729 | PREVCOP_03926 | Hypothetical protein. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: eci:UTI89_C0501 4.4e-67 htpG; chaperone HSP90, heat shock protein C 62.5 K04079; Psort location: Cytoplasmic, score: 9.26. | 0.970 |
EFB34749.1 | dnaJ | PREVCOP_05729 | PREVCOP_04050 | Hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.875 |
EFB34749.1 | groL | PREVCOP_05729 | PREVCOP_03551 | Hypothetical protein. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.850 |
EFB34749.1 | groS | PREVCOP_05729 | PREVCOP_03550 | Hypothetical protein. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.803 |
EFB34749.1 | grpE | PREVCOP_05729 | PREVCOP_04049 | Hypothetical protein. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.934 |
EFB34749.1 | lon | PREVCOP_05729 | PREVCOP_06441 | Hypothetical protein. | Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.467 |
EFB35735.1 | EFB34749.1 | PREVCOP_04639 | PREVCOP_05729 | DnaJ domain protein. | Hypothetical protein. | 0.893 |
EFB35735.1 | EFB35983.1 | PREVCOP_04639 | PREVCOP_04402 | DnaJ domain protein. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96; Belongs to the heat shock protein 70 family. | 0.893 |
EFB35735.1 | EFB36548.1 | PREVCOP_04639 | PREVCOP_03926 | DnaJ domain protein. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: eci:UTI89_C0501 4.4e-67 htpG; chaperone HSP90, heat shock protein C 62.5 K04079; Psort location: Cytoplasmic, score: 9.26. | 0.941 |
EFB35735.1 | dnaK | PREVCOP_04639 | PREVCOP_05789 | DnaJ domain protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.914 |
EFB35735.1 | groL | PREVCOP_04639 | PREVCOP_03551 | DnaJ domain protein. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.645 |
EFB35735.1 | groS | PREVCOP_04639 | PREVCOP_03550 | DnaJ domain protein. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.582 |
EFB35735.1 | grpE | PREVCOP_04639 | PREVCOP_04049 | DnaJ domain protein. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.842 |
EFB35735.1 | lon | PREVCOP_04639 | PREVCOP_06441 | DnaJ domain protein. | Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.575 |
EFB35983.1 | EFB35735.1 | PREVCOP_04402 | PREVCOP_04639 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96; Belongs to the heat shock protein 70 family. | DnaJ domain protein. | 0.893 |
EFB35983.1 | EFB36483.1 | PREVCOP_04402 | PREVCOP_03861 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96; Belongs to the heat shock protein 70 family. | DnaJ domain protein; KEGG: cme:CMJ043C 4.4e-07 phycocyanobilin lyase alpha subunit K02288; Psort location: Cytoplasmic, score: 9.26. | 0.875 |
EFB35983.1 | EFB36548.1 | PREVCOP_04402 | PREVCOP_03926 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96; Belongs to the heat shock protein 70 family. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: eci:UTI89_C0501 4.4e-67 htpG; chaperone HSP90, heat shock protein C 62.5 K04079; Psort location: Cytoplasmic, score: 9.26. | 0.970 |
EFB35983.1 | dnaJ | PREVCOP_04402 | PREVCOP_04050 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96; Belongs to the heat shock protein 70 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.875 |