| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFB35272.1 | glyA | PREVCOP_05410 | PREVCOP_04258 | KEGG: pgi:PG0752 4.5e-65 uracil phosphoribosyltransferase, putative K00761. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.747 |
| EFB35272.1 | rpiB | PREVCOP_05410 | PREVCOP_04063 | KEGG: pgi:PG0752 4.5e-65 uracil phosphoribosyltransferase, putative K00761. | KEGG: bth:BT0346 2.7e-51 ribose 5-phosphate isomerase B K01808; Psort location: Cytoplasmic, score: 8.96. | 0.896 |
| EFB36114.1 | glyA | PREVCOP_04537 | PREVCOP_04258 | Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: mca:MCA1545 3.8e-49 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.96. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.786 |
| EFB36114.1 | nifJ | PREVCOP_04537 | PREVCOP_03943 | Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: mca:MCA1545 3.8e-49 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.96. | Pyruvate synthase; KEGG: bfs:BF3168 0. nifJ; putative pyruvate-flavodoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 8.96. | 0.929 |
| EFB36114.1 | rpiB | PREVCOP_04537 | PREVCOP_04063 | Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: mca:MCA1545 3.8e-49 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT0346 2.7e-51 ribose 5-phosphate isomerase B K01808; Psort location: Cytoplasmic, score: 8.96. | 0.725 |
| EFB36321.1 | EFB36368.1 | PREVCOP_04210 | PREVCOP_04062 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: bth:BT1548 1.0e-209 phosphoglucomutase phosphomannomutase K01840. | Transketolase, thiamine diphosphate binding domain protein; KEGG: bth:BT0347 2.2e-285 transketolase K00615; Belongs to the transketolase family. | 0.894 |
| EFB36321.1 | prs | PREVCOP_04210 | PREVCOP_06835 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: bth:BT1548 1.0e-209 phosphoglucomutase phosphomannomutase K01840. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.908 |
| EFB36321.1 | rpe | PREVCOP_04210 | PREVCOP_03582 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: bth:BT1548 1.0e-209 phosphoglucomutase phosphomannomutase K01840. | KEGG: bfr:BF3902 1.5e-71 ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 8.96. | 0.462 |
| EFB36321.1 | rpiB | PREVCOP_04210 | PREVCOP_04063 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: bth:BT1548 1.0e-209 phosphoglucomutase phosphomannomutase K01840. | KEGG: bth:BT0346 2.7e-51 ribose 5-phosphate isomerase B K01808; Psort location: Cytoplasmic, score: 8.96. | 0.884 |
| EFB36368.1 | EFB36321.1 | PREVCOP_04062 | PREVCOP_04210 | Transketolase, thiamine diphosphate binding domain protein; KEGG: bth:BT0347 2.2e-285 transketolase K00615; Belongs to the transketolase family. | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: bth:BT1548 1.0e-209 phosphoglucomutase phosphomannomutase K01840. | 0.894 |
| EFB36368.1 | glyA | PREVCOP_04062 | PREVCOP_04258 | Transketolase, thiamine diphosphate binding domain protein; KEGG: bth:BT0347 2.2e-285 transketolase K00615; Belongs to the transketolase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.409 |
| EFB36368.1 | nifJ | PREVCOP_04062 | PREVCOP_03943 | Transketolase, thiamine diphosphate binding domain protein; KEGG: bth:BT0347 2.2e-285 transketolase K00615; Belongs to the transketolase family. | Pyruvate synthase; KEGG: bfs:BF3168 0. nifJ; putative pyruvate-flavodoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 8.96. | 0.922 |
| EFB36368.1 | prs | PREVCOP_04062 | PREVCOP_06835 | Transketolase, thiamine diphosphate binding domain protein; KEGG: bth:BT0347 2.2e-285 transketolase K00615; Belongs to the transketolase family. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.940 |
| EFB36368.1 | rpe | PREVCOP_04062 | PREVCOP_03582 | Transketolase, thiamine diphosphate binding domain protein; KEGG: bth:BT0347 2.2e-285 transketolase K00615; Belongs to the transketolase family. | KEGG: bfr:BF3902 1.5e-71 ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 8.96. | 0.974 |
| EFB36368.1 | rpiB | PREVCOP_04062 | PREVCOP_04063 | Transketolase, thiamine diphosphate binding domain protein; KEGG: bth:BT0347 2.2e-285 transketolase K00615; Belongs to the transketolase family. | KEGG: bth:BT0346 2.7e-51 ribose 5-phosphate isomerase B K01808; Psort location: Cytoplasmic, score: 8.96. | 0.963 |
| EFB36488.1 | rpiB | PREVCOP_03866 | PREVCOP_04063 | SAF domain protein; KEGG: bth:BT0486 2.4e-194 altronate hydrolase K01685. | KEGG: bth:BT0346 2.7e-51 ribose 5-phosphate isomerase B K01808; Psort location: Cytoplasmic, score: 8.96. | 0.813 |
| EFB36488.1 | uxuA | PREVCOP_03866 | PREVCOP_05093 | SAF domain protein; KEGG: bth:BT0486 2.4e-194 altronate hydrolase K01685. | Putative mannonate dehydratase; Catalyzes the dehydration of D-mannonate. | 0.939 |
| glyA | EFB35272.1 | PREVCOP_04258 | PREVCOP_05410 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | KEGG: pgi:PG0752 4.5e-65 uracil phosphoribosyltransferase, putative K00761. | 0.747 |
| glyA | EFB36114.1 | PREVCOP_04258 | PREVCOP_04537 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: mca:MCA1545 3.8e-49 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.96. | 0.786 |
| glyA | EFB36368.1 | PREVCOP_04258 | PREVCOP_04062 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Transketolase, thiamine diphosphate binding domain protein; KEGG: bth:BT0347 2.2e-285 transketolase K00615; Belongs to the transketolase family. | 0.409 |