STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFB36404.1LeuA allosteric (dimerization) domain protein; KEGG: bth:BT1858 3.2e-190 2-isopropylmalate synthase K01649; Belongs to the alpha-IPM synthase/homocitrate synthase family. (532 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.997
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.994
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family.
 
 0.950
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 
 
0.947
nifJ
Pyruvate synthase; KEGG: bfs:BF3168 0. nifJ; putative pyruvate-flavodoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.945
ilvN
KEGG: bth:BT2076 1.3e-53 acetohydroxyacid synthase small subunit K01653; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.923
ilvD
KEGG: bfr:BF3763 8.1e-249 dihydroxy-acid dehydratase K01687; Psort location: Cytoplasmic, score: 8.96; Belongs to the IlvD/Edd family.
  
 
 0.898
ilvB
Acetolactate synthase, large subunit, biosynthetic type; KEGG: bth:BT2077 2.4e-208 acetolactate synthase large subunit K01652.
 
 
 0.882
EFB34565.1
Phosphate acetyl/butyryl transferase; KEGG: bfs:BF3408 0. maeB; putative NADP-dependent malic enzyme K00029; Psort location: Cytoplasmic, score: 8.96.
   
 
 0.771
pyk
Pyruvate kinase; KEGG: bfr:BF4482 3.8e-148 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 8.96.
     
 0.760
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.