STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recQKEGG: bth:BT1848 7.2e-193 recQ; ATP-dependent DNA helicase recQ K03654; Psort location: Cytoplasmic, score: 8.96. (620 aa)    
Predicted Functional Partners:
EFB35402.1
KEGG: bth:BT2089 3.1e-240 DNA topoisomerase III K03169; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.948
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.920
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.858
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 0.855
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.836
EFB36297.1
KEGG: eci:UTI89_C0417 2.8e-79 sbcC; exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 9.26.
   
 0.791
EFB36431.1
Hypothetical protein.
       0.773
EFB36309.1
UvrD/REP helicase; KEGG: bfs:BF2555 4.4e-225 putative helicase K03657.
 
 0.722
EFB34637.1
Hypothetical protein; KEGG: ayw:AYWB_115 1.6e-08 uvrD; UvrD helicase K03657.
  
 0.722
EFB36430.1
Peptidase family M49; KEGG: bth:BT1846 8.7e-220 putative dipeptidyl-peptidase III K01277; Psort location: Cytoplasmic, score: 8.96.
   
   0.709
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
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