STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFB36283.1ThiF family protein; KEGG: hpa:HPAG1_0799 1.2e-66 thiamine biosynthesis protein; Psort location: Cytoplasmic, score: 8.96. (269 aa)    
Predicted Functional Partners:
thiS
Thiamine biosynthesis protein ThiS; Psort location: Cytoplasmic, score: 8.96.
  
 0.949
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.918
EFB33671.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: bce:BC0791 5.7e-145 NADH dehydrogenase K00359; Psort location: Cytoplasmic, score: 9.26; Belongs to the sulfur carrier protein TusA family.
  
 
 0.891
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.714
EFB36659.1
ThiF family protein; KEGG: cal:orf19.2115 7.9e-29 molybdopterin-converting factor; Psort location: Cytoplasmic, score: 8.96.
 
0.670
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 
  0.662
EFB36890.1
Thiamine monophosphate synthase/TENI; KEGG: chu:CHU_0246 2.4e-11 thiE; thiamine phosphate pyrophosphorylase K00788; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.572
trxB
KEGG: pgi:PG1134 1.9e-112 trxB; thioredoxin reductase K00384; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.567
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 
 0.558
EFB33722.1
Hypothetical protein; KEGG: chu:CHU_0246 9.5e-06 thiE; thiamine phosphate pyrophosphorylase K00788; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.543
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
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