STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFB36297.1KEGG: eci:UTI89_C0417 2.8e-79 sbcC; exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 9.26. (1151 aa)    
Predicted Functional Partners:
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
 0.999
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.980
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.870
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.818
EFB35402.1
KEGG: bth:BT2089 3.1e-240 DNA topoisomerase III K03169; Psort location: Cytoplasmic, score: 8.96.
  
 0.804
recQ
KEGG: bth:BT1848 7.2e-193 recQ; ATP-dependent DNA helicase recQ K03654; Psort location: Cytoplasmic, score: 8.96.
   
 0.791
EFB35764.1
KEGG: bth:BT3938 1.1e-194 recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 8.96.
   
 0.791
recQ-2
KEGG: bfr:BF4076 2.6e-291 recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 8.96.
   
 0.791
EFB36683.1
FHA domain protein.
    
 0.740
asnS
asparagine--tRNA ligase; KEGG: bfr:BF4016 2.3e-189 asparaginyl-tRNA synthetase K01893; Psort location: Cytoplasmic, score: 9.26.
  
 
  0.655
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.