| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFB34510.1 | EFB36113.1 | PREVCOP_05944 | PREVCOP_04536 | ATP-grasp domain protein; KEGG: reh:H16_A2106 1.1e-22 carB1; carbamoylphosphate synthase, large subunit K01954; Psort location: Cytoplasmic, score: 8.96. | Amidohydrolase family protein; KEGG: bth:BT0250 2.4e-130 dihydroorotase (DHOase) K01465; Psort location: Cytoplasmic, score: 8.96. | 0.717 |
| EFB34510.1 | carA | PREVCOP_05944 | PREVCOP_04711 | ATP-grasp domain protein; KEGG: reh:H16_A2106 1.1e-22 carB1; carbamoylphosphate synthase, large subunit K01954; Psort location: Cytoplasmic, score: 8.96. | Carbamoyl-phosphate synthase, small subunit; KEGG: bfr:BF2636 1.5e-160 glutamine-hydrolyzing carbamoyl phosphate synthetase III K01956; Psort location: Cytoplasmic, score: 8.96; Belongs to the CarA family. | 0.968 |
| EFB34510.1 | pbuX | PREVCOP_05944 | PREVCOP_04984 | ATP-grasp domain protein; KEGG: reh:H16_A2106 1.1e-22 carB1; carbamoylphosphate synthase, large subunit K01954; Psort location: Cytoplasmic, score: 8.96. | Xanthine permease; KEGG: mle:ML2279 3.2e-07 putative transmembrane transport protein K01672; Psort location: CytoplasmicMembrane, score: 10.00. | 0.639 |
| EFB34510.1 | pyrB | PREVCOP_05944 | PREVCOP_04256 | ATP-grasp domain protein; KEGG: reh:H16_A2106 1.1e-22 carB1; carbamoylphosphate synthase, large subunit K01954; Psort location: Cytoplasmic, score: 8.96. | KEGG: bfr:BF2208 4.7e-134 aspartate carbamoyltransferase catalytic chain K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.938 |
| EFB34510.1 | pyrD | PREVCOP_05944 | PREVCOP_04650 | ATP-grasp domain protein; KEGG: reh:H16_A2106 1.1e-22 carB1; carbamoylphosphate synthase, large subunit K01954; Psort location: Cytoplasmic, score: 8.96. | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | 0.796 |
| EFB34510.1 | pyrE | PREVCOP_05944 | PREVCOP_05365 | ATP-grasp domain protein; KEGG: reh:H16_A2106 1.1e-22 carB1; carbamoylphosphate synthase, large subunit K01954; Psort location: Cytoplasmic, score: 8.96. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.728 |
| EFB34510.1 | pyrF | PREVCOP_05944 | PREVCOP_04518 | ATP-grasp domain protein; KEGG: reh:H16_A2106 1.1e-22 carB1; carbamoylphosphate synthase, large subunit K01954; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT4209 5.1e-105 orotidine 5'-phosphate decarboxylase K01591; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.699 |
| EFB34510.1 | pyrI | PREVCOP_05944 | PREVCOP_04257 | ATP-grasp domain protein; KEGG: reh:H16_A2106 1.1e-22 carB1; carbamoylphosphate synthase, large subunit K01954; Psort location: Cytoplasmic, score: 8.96. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.886 |
| EFB36113.1 | EFB34510.1 | PREVCOP_04536 | PREVCOP_05944 | Amidohydrolase family protein; KEGG: bth:BT0250 2.4e-130 dihydroorotase (DHOase) K01465; Psort location: Cytoplasmic, score: 8.96. | ATP-grasp domain protein; KEGG: reh:H16_A2106 1.1e-22 carB1; carbamoylphosphate synthase, large subunit K01954; Psort location: Cytoplasmic, score: 8.96. | 0.717 |
| EFB36113.1 | carA | PREVCOP_04536 | PREVCOP_04711 | Amidohydrolase family protein; KEGG: bth:BT0250 2.4e-130 dihydroorotase (DHOase) K01465; Psort location: Cytoplasmic, score: 8.96. | Carbamoyl-phosphate synthase, small subunit; KEGG: bfr:BF2636 1.5e-160 glutamine-hydrolyzing carbamoyl phosphate synthetase III K01956; Psort location: Cytoplasmic, score: 8.96; Belongs to the CarA family. | 0.995 |
| EFB36113.1 | carB | PREVCOP_04536 | PREVCOP_04712 | Amidohydrolase family protein; KEGG: bth:BT0250 2.4e-130 dihydroorotase (DHOase) K01465; Psort location: Cytoplasmic, score: 8.96. | Carbamoyl-phosphate synthase, large subunit; KEGG: bfr:BF2635 0. carbamyl phosphate synthetase K01955; Psort location: Cytoplasmic, score: 8.96. | 0.971 |
| EFB36113.1 | carB-2 | PREVCOP_04536 | PREVCOP_05066 | Amidohydrolase family protein; KEGG: bth:BT0250 2.4e-130 dihydroorotase (DHOase) K01465; Psort location: Cytoplasmic, score: 8.96. | Carbamoyl-phosphate synthase, large subunit; KEGG: bfr:BF4035 0. glutamine-dependent carbamyl phosphate synthetase K01955; Psort location: Cytoplasmic, score: 8.96. | 0.974 |
| EFB36113.1 | pbuX | PREVCOP_04536 | PREVCOP_04984 | Amidohydrolase family protein; KEGG: bth:BT0250 2.4e-130 dihydroorotase (DHOase) K01465; Psort location: Cytoplasmic, score: 8.96. | Xanthine permease; KEGG: mle:ML2279 3.2e-07 putative transmembrane transport protein K01672; Psort location: CytoplasmicMembrane, score: 10.00. | 0.809 |
| EFB36113.1 | pyrB | PREVCOP_04536 | PREVCOP_04256 | Amidohydrolase family protein; KEGG: bth:BT0250 2.4e-130 dihydroorotase (DHOase) K01465; Psort location: Cytoplasmic, score: 8.96. | KEGG: bfr:BF2208 4.7e-134 aspartate carbamoyltransferase catalytic chain K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| EFB36113.1 | pyrD | PREVCOP_04536 | PREVCOP_04650 | Amidohydrolase family protein; KEGG: bth:BT0250 2.4e-130 dihydroorotase (DHOase) K01465; Psort location: Cytoplasmic, score: 8.96. | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | 0.997 |
| EFB36113.1 | pyrE | PREVCOP_04536 | PREVCOP_05365 | Amidohydrolase family protein; KEGG: bth:BT0250 2.4e-130 dihydroorotase (DHOase) K01465; Psort location: Cytoplasmic, score: 8.96. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.977 |
| EFB36113.1 | pyrF | PREVCOP_04536 | PREVCOP_04518 | Amidohydrolase family protein; KEGG: bth:BT0250 2.4e-130 dihydroorotase (DHOase) K01465; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT4209 5.1e-105 orotidine 5'-phosphate decarboxylase K01591; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.948 |
| EFB36113.1 | pyrI | PREVCOP_04536 | PREVCOP_04257 | Amidohydrolase family protein; KEGG: bth:BT0250 2.4e-130 dihydroorotase (DHOase) K01465; Psort location: Cytoplasmic, score: 8.96. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.942 |
| carA | EFB34510.1 | PREVCOP_04711 | PREVCOP_05944 | Carbamoyl-phosphate synthase, small subunit; KEGG: bfr:BF2636 1.5e-160 glutamine-hydrolyzing carbamoyl phosphate synthetase III K01956; Psort location: Cytoplasmic, score: 8.96; Belongs to the CarA family. | ATP-grasp domain protein; KEGG: reh:H16_A2106 1.1e-22 carB1; carbamoylphosphate synthase, large subunit K01954; Psort location: Cytoplasmic, score: 8.96. | 0.968 |
| carA | EFB36113.1 | PREVCOP_04711 | PREVCOP_04536 | Carbamoyl-phosphate synthase, small subunit; KEGG: bfr:BF2636 1.5e-160 glutamine-hydrolyzing carbamoyl phosphate synthetase III K01956; Psort location: Cytoplasmic, score: 8.96; Belongs to the CarA family. | Amidohydrolase family protein; KEGG: bth:BT0250 2.4e-130 dihydroorotase (DHOase) K01465; Psort location: Cytoplasmic, score: 8.96. | 0.995 |