STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFB36258.1O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: bth:BT1923 8.9e-179 O-acetylhomoserine (thiol)-lyase K01740; Psort location: Cytoplasmic, score: 9.97. (437 aa)    
Predicted Functional Partners:
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.896
EFB35841.1
Cys/Met metabolism PLP-dependent enzyme; KEGG: ilo:IL2014 1.5e-27 O-acetylhomoserine sulfhydrylase K01740; Psort location: Cytoplasmic, score: 9.26.
  
  
 
0.870
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 
 0.851
EFB36114.1
Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: mca:MCA1545 3.8e-49 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.842
EFB34481.1
KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase.
  
 
 0.823
EFB36257.1
Hypothetical protein.
       0.773
EFB33671.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: bce:BC0791 5.7e-145 NADH dehydrogenase K00359; Psort location: Cytoplasmic, score: 9.26; Belongs to the sulfur carrier protein TusA family.
    
 0.769
cysK
Cysteine synthase A; KEGG: bth:BT3080 2.2e-120 cysteine synthase A K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.749
EFB34457.1
Aminotransferase, class I/II; KEGG: bth:BT1398 7.1e-131 putative aminotransferase B K00842; Psort location: Cytoplasmic, score: 8.96.
   
 0.727
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
 0.695
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
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