STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFB36003.1Transcriptional regulator, MerR family; KEGG: vfi:VFA0114 7.4e-05 methyltransferase K00599. (115 aa)    
Predicted Functional Partners:
EFB34847.1
Class II glutamine amidotransferase; KEGG: bth:BT0553 0. glutamate synthase, large subunit K00265; Psort location: Cytoplasmic, score: 8.96.
    
 0.897
EFB36492.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: dvu:DVU2587 1.2e-13 sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 9.46.
   
 0.830
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.808
EFB36224.1
KEGG: ava:Ava_2150 2.8e-16 response regulator receiver signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.97.
   
 0.805
EFB35735.1
DnaJ domain protein.
  
 
 0.792
EFB36483.1
DnaJ domain protein; KEGG: cme:CMJ043C 4.4e-07 phycocyanobilin lyase alpha subunit K02288; Psort location: Cytoplasmic, score: 9.26.
  
 
 0.791
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.791
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.761
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.746
EFB34190.1
Hypothetical protein.
   
 
 0.746
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
Server load: low (26%) [HD]