STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFB36100.1KEGG: bfs:BF0838 3.7e-86 aroE; putative shikimate 5-dehydrogenase K00014. (248 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 0.982
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 
 0.981
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 0.970
aroQ
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
 
 
 0.967
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 0.958
EFB35751.1
Putative 3-deoxy-7-phosphoheptulonate synthase; KEGG: bfs:BF3717 1.6e-142 putative chorismate mutase K04516:K03856; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.912
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
  
  
 0.838
EFB36949.1
Glutamine amidotransferase, class I; KEGG: bth:BT0531 1.6e-69 anthranilate synthase component II K01658; Psort location: Cytoplasmic, score: 8.96.
 
 0.831
purC
KEGG: bfr:BF0918 2.6e-124 phosphoribosylamidoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 8.96; Belongs to the SAICAR synthetase family.
       0.806
EFB36099.1
Hypothetical protein; KEGG: bfr:BF0911 1.7e-175 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.96.
     
 0.722
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
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