| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFB34481.1 | EFB36119.1 | PREVCOP_06054 | PREVCOP_04542 | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.579 |
| EFB34481.1 | glyA | PREVCOP_06054 | PREVCOP_04258 | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.834 |
| EFB34481.1 | ilvA | PREVCOP_06054 | PREVCOP_05330 | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | KEGG: tma:TM0356 4.4e-106 threonine dehydratase catabolic K01754; Psort location: Cytoplasmic, score: 8.96. | 0.964 |
| EFB34481.1 | menG | PREVCOP_06054 | PREVCOP_04523 | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.500 |
| EFB34481.1 | trpA | PREVCOP_06054 | PREVCOP_03588 | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.877 |
| EFB34481.1 | trpB | PREVCOP_06054 | PREVCOP_03589 | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.841 |
| EFB34481.1 | trpF | PREVCOP_06054 | PREVCOP_03587 | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | KEGG: bfr:BF2655 1.2e-48 putative N-(5'-phosphoribosyl)anthranilate isomerase K01817; Psort location: Cytoplasmic, score: 8.96; Belongs to the TrpF family. | 0.792 |
| EFB36119.1 | EFB34481.1 | PREVCOP_04542 | PREVCOP_06054 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | 0.579 |
| EFB36119.1 | EFB36120.1 | PREVCOP_04542 | PREVCOP_04543 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Hypothetical protein. | 0.773 |
| EFB36119.1 | glyA | PREVCOP_04542 | PREVCOP_04258 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.877 |
| EFB36119.1 | ilvA | PREVCOP_04542 | PREVCOP_05330 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | KEGG: tma:TM0356 4.4e-106 threonine dehydratase catabolic K01754; Psort location: Cytoplasmic, score: 8.96. | 0.742 |
| EFB36119.1 | menG | PREVCOP_04542 | PREVCOP_04523 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.416 |
| EFB36119.1 | trpA | PREVCOP_04542 | PREVCOP_03588 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.991 |
| EFB36119.1 | trpB | PREVCOP_04542 | PREVCOP_03589 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.839 |
| EFB36119.1 | trpC | PREVCOP_04542 | PREVCOP_03586 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | KEGG: bth:BT0529 6.2e-68 indole-3-glycerol phosphate synthase K01609; Psort location: Cytoplasmic, score: 8.96; Belongs to the TrpC family. | 0.907 |
| EFB36119.1 | trpF | PREVCOP_04542 | PREVCOP_03587 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | KEGG: bfr:BF2655 1.2e-48 putative N-(5'-phosphoribosyl)anthranilate isomerase K01817; Psort location: Cytoplasmic, score: 8.96; Belongs to the TrpF family. | 0.512 |
| EFB36120.1 | EFB36119.1 | PREVCOP_04543 | PREVCOP_04542 | Hypothetical protein. | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.773 |
| glyA | EFB34481.1 | PREVCOP_04258 | PREVCOP_06054 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | 0.834 |
| glyA | EFB36119.1 | PREVCOP_04258 | PREVCOP_04542 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.877 |
| glyA | ilvA | PREVCOP_04258 | PREVCOP_05330 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | KEGG: tma:TM0356 4.4e-106 threonine dehydratase catabolic K01754; Psort location: Cytoplasmic, score: 8.96. | 0.820 |