STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (428 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
EFB34847.1
Class II glutamine amidotransferase; KEGG: bth:BT0553 0. glutamate synthase, large subunit K00265; Psort location: Cytoplasmic, score: 8.96.
    
 0.938
nifJ
Pyruvate synthase; KEGG: bfs:BF3168 0. nifJ; putative pyruvate-flavodoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 8.96.
   
  0.807
argF
KEGG: bth:BT3717 5.1e-128 ornithine carbamoyltransferase K00611; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
  
  
 0.788
gdhA
KEGG: bfr:BF3607 7.3e-200 NADP-specific glutamate dehydrogenase K00262; Psort location: Cytoplasmic, score: 9.26; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.730
purL
Putative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
 
 0.723
gltA
KEGG: bth:BT4310 0. NADPH-dependent glutamate synthase small chain K00266; Psort location: Cytoplasmic, score: 9.97.
    
 0.714
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
 
    
 0.696
proC
Putative pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.664
EFB35544.1
Aminotransferase, class III; KEGG: bfs:BF0479 1.3e-147 argD; putative acetylornithine aminotransferase K00818; Psort location: Cytoplasmic, score: 8.96; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 0.656
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
Server load: low (24%) [HD]