| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFB34361.1 | folB | PREVCOP_06080 | PREVCOP_05123 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: tbd:Tbd_2051 1.1e-08 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK K00950. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.963 |
| EFB34361.1 | folC | PREVCOP_06080 | PREVCOP_04051 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: tbd:Tbd_2051 1.1e-08 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK K00950. | Bifunctional protein FolC; KEGG: bfr:BF2974 1.6e-117 folylpolyglutamate synthase K01930; Psort location: Cytoplasmic, score: 8.96. | 0.627 |
| EFB34361.1 | folE | PREVCOP_06080 | PREVCOP_06384 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: tbd:Tbd_2051 1.1e-08 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK K00950. | GTP cyclohydrolase I; KEGG: bfs:BF3727 5.1e-73 folE, mtrA; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96. | 0.724 |
| EFB34361.1 | folP | PREVCOP_06080 | PREVCOP_04868 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: tbd:Tbd_2051 1.1e-08 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK K00950. | KEGG: bth:BT3646 2.0e-78 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 8.96. | 0.963 |
| EFB34481.1 | EFB36058.1 | PREVCOP_06054 | PREVCOP_04480 | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | Hypothetical protein; KEGG: bfs:BF2336 3.9e-43 putative para-aminobenzoate synthase component I K02619; Psort location: Cytoplasmic, score: 8.96. | 0.881 |
| EFB34481.1 | folP | PREVCOP_06054 | PREVCOP_04868 | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | KEGG: bth:BT3646 2.0e-78 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 8.96. | 0.615 |
| EFB34481.1 | guaB | PREVCOP_06054 | PREVCOP_05652 | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.864 |
| EFB36058.1 | EFB34481.1 | PREVCOP_04480 | PREVCOP_06054 | Hypothetical protein; KEGG: bfs:BF2336 3.9e-43 putative para-aminobenzoate synthase component I K02619; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT2403 1.8e-299 homoserine dehydrogenase. | 0.881 |
| EFB36058.1 | folP | PREVCOP_04480 | PREVCOP_04868 | Hypothetical protein; KEGG: bfs:BF2336 3.9e-43 putative para-aminobenzoate synthase component I K02619; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT3646 2.0e-78 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 8.96. | 0.946 |
| dacA | folP | PREVCOP_04867 | PREVCOP_04868 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | KEGG: bth:BT3646 2.0e-78 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 8.96. | 0.824 |
| dacA | pta | PREVCOP_04867 | PREVCOP_04866 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | KEGG: bth:BT3692 3.8e-116 phosphate acetyltransferase K00625. | 0.589 |
| folB | EFB34361.1 | PREVCOP_05123 | PREVCOP_06080 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: tbd:Tbd_2051 1.1e-08 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK K00950. | 0.963 |
| folB | folC | PREVCOP_05123 | PREVCOP_04051 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Bifunctional protein FolC; KEGG: bfr:BF2974 1.6e-117 folylpolyglutamate synthase K01930; Psort location: Cytoplasmic, score: 8.96. | 0.768 |
| folB | folE | PREVCOP_05123 | PREVCOP_06384 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; KEGG: bfs:BF3727 5.1e-73 folE, mtrA; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96. | 0.975 |
| folB | folK | PREVCOP_05123 | PREVCOP_06399 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: bth:BT3216 1.0e-33 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine K00950; Psort location: Cytoplasmic, score: 8.96. | 0.994 |
| folB | folP | PREVCOP_05123 | PREVCOP_04868 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: bth:BT3646 2.0e-78 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 8.96. | 0.997 |
| folC | EFB34361.1 | PREVCOP_04051 | PREVCOP_06080 | Bifunctional protein FolC; KEGG: bfr:BF2974 1.6e-117 folylpolyglutamate synthase K01930; Psort location: Cytoplasmic, score: 8.96. | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: tbd:Tbd_2051 1.1e-08 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK K00950. | 0.627 |
| folC | folB | PREVCOP_04051 | PREVCOP_05123 | Bifunctional protein FolC; KEGG: bfr:BF2974 1.6e-117 folylpolyglutamate synthase K01930; Psort location: Cytoplasmic, score: 8.96. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.768 |
| folC | folE | PREVCOP_04051 | PREVCOP_06384 | Bifunctional protein FolC; KEGG: bfr:BF2974 1.6e-117 folylpolyglutamate synthase K01930; Psort location: Cytoplasmic, score: 8.96. | GTP cyclohydrolase I; KEGG: bfs:BF3727 5.1e-73 folE, mtrA; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96. | 0.585 |
| folC | folK | PREVCOP_04051 | PREVCOP_06399 | Bifunctional protein FolC; KEGG: bfr:BF2974 1.6e-117 folylpolyglutamate synthase K01930; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT3216 1.0e-33 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine K00950; Psort location: Cytoplasmic, score: 8.96. | 0.716 |