STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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Coexpression
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[Homology]
Score
pdxSPyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (291 aa)    
Predicted Functional Partners:
pdxT
Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
 0.999
EFB33901.1
KEGG: cac:CAC1622 2.3e-38 pyridoxal kinase related protein K00868; Psort location: Cytoplasmic, score: 8.96.
    
 0.887
EFB36368.1
Transketolase, thiamine diphosphate binding domain protein; KEGG: bth:BT0347 2.2e-285 transketolase K00615; Belongs to the transketolase family.
   
 
  0.878
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 
  0.873
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: bth:BT4263 1.7e-136 glyceraldehyde 3-phosphate dehydrogenase K00134; Psort location: Cytoplasmic, score: 9.97; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
  
 0.813
EFB35595.1
KEGG: bth:BT0790 3.3e-37 phosphomethylpyrimidine kinase K00877:K00941; Psort location: Cytoplasmic, score: 8.96.
    
 0.696
EFB36489.1
KEGG: efa:EF1922 2.6e-05 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; Psort location: Cytoplasmic, score: 9.97.
    
  0.509
EFB35345.1
Sugar-binding domain protein; KEGG: efa:EF1922 2.1e-11 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; Psort location: Cytoplasmic, score: 9.97.
    
  0.509
EFB34692.1
KEGG: efa:EF1922 0.0011 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; Psort location: Cytoplasmic, score: 9.97.
    
  0.509
thrC
Threonine synthase; KEGG: bfs:BF0560 2.3e-180 thrC; threonine synthase K01733; Psort location: Cytoplasmic, score: 8.96.
   
    0.506
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
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