STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (345 aa)    
Predicted Functional Partners:
ribE
KEGG: bth:BT1317 2.5e-80 riboflavin synthase alpha chain K00793; Psort location: Cytoplasmic, score: 8.96.
 
 0.999
ribB
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.996
EFB36562.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
   
   0.920
folE
GTP cyclohydrolase I; KEGG: bfs:BF3727 5.1e-73 folE, mtrA; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96.
    
 0.852
EFB35924.1
acyl-CoA dehydrogenase, C-terminal domain protein; KEGG: bth:BT1806 7.5e-214 acyl-CoA dehydrogenase K00257; Psort location: Cytoplasmic, score: 8.96.
  
 0.779
EFB36079.1
Hypothetical protein; KEGG: aha:AHA_2647 5.1e-18 esterase YdiI.
    
 0.771
EFB36647.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
    
 0.742
EFB35193.1
Cof-like hydrolase; KEGG: btk:BT9727_5077 2.8e-49 hydrolase, haloacid dehalogenase-like family; Psort location: Cytoplasmic, score: 8.96.
    
 0.742
EFB34092.1
Cof-like hydrolase; KEGG: eci:UTI89_C4247 4.3e-21 yidA; hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
    
 0.742
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
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