STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFB35026.16-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (177 aa)    
Predicted Functional Partners:
EFB36776.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
      0.833
EFB35027.1
Hypothetical protein.
       0.701
EFB35025.1
Glyoxalase family protein; KEGG: bat:BAS0574 7.5e-40 glyoxylase family protein K01759; Psort location: Cytoplasmic, score: 8.96.
       0.694
lpxB
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
      0.619
nhaC
Na+/H+ antiporter NhaC; Psort location: CytoplasmicMembrane, score: 10.00.
       0.609
EFB35029.1
Hypothetical protein.
       0.501
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.430
EFB36613.1
Sigma-70 region 2; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
   0.407
EFB36617.1
Sigma-70 region 2; KEGG: hpa:HPAG1_0089 2.3e-14 RNA polymerase sigma-80 factor K00960; Psort location: Cytoplasmic, score: 9.97; Belongs to the sigma-70 factor family.
    
   0.407
EFB36173.1
Sigma-70 region 2; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
   0.407
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.