STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiHThiazole biosynthesis protein ThiH; KEGG: mac:MA0154 9.4e-10 bioB; biotin synthase K01012. (379 aa)    
Predicted Functional Partners:
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.993
EFB35160.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: reh:H16_A0828 4.8e-41 cycS1; signal transduction histidine kinase containing a receiver domain (hybrid) and a PAS sensor domain; Psort location: CytoplasmicMembrane, score: 7.88.
  
    0.936
thiS
Thiamine biosynthesis protein ThiS; Psort location: Cytoplasmic, score: 8.96.
 
 
  0.900
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.900
EFB36890.1
Thiamine monophosphate synthase/TENI; KEGG: chu:CHU_0246 2.4e-11 thiE; thiamine phosphate pyrophosphorylase K00788; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.891
EFB33722.1
Hypothetical protein; KEGG: chu:CHU_0246 9.5e-06 thiE; thiamine phosphate pyrophosphorylase K00788; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.800
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.715
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
     
 0.561
EFB36283.1
ThiF family protein; KEGG: hpa:HPAG1_0799 1.2e-66 thiamine biosynthesis protein; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.514
EFB36221.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.458
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
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