STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdDKEGG: bfs:BF3484 2.2e-166 putative anaerobic ribonucleoside-triphosphate reductase K00527; Psort location: Cytoplasmic, score: 8.96. (739 aa)    
Predicted Functional Partners:
EFB34360.1
Hypothetical protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
 
 
 0.995
dut
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
    
 0.895
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.884
ribB
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.873
EFB36492.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: dvu:DVU2587 1.2e-13 sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 9.46.
  
 
  0.770
EFB34072.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ava:Ava_2239 9.6e-62 adenylate/guanylate cyclase K01768; Psort location: CytoplasmicMembrane, score: 7.88.
     
 0.562
EFB34078.1
Transcriptional regulator, AraC family; KEGG: msm:MSMEG_3095 4.6e-11 D-ribose-binding periplasmic protein; Psort location: Periplasmic, score: 9.44.
     
 0.562
EFB35457.1
Hypothetical protein; KEGG: bth:BT2145 9.6e-65 ribonucleoside-diphosphate reductase alpha chain K00525.
  
 
 0.553
EFB35358.1
Putative CoA-substrate-specific enzyme activase; KEGG: rpa:RPA0659 8.1e-18 badF; benzoyl-CoA reductase subunit K04114.
 
     0.491
EFB34847.1
Class II glutamine amidotransferase; KEGG: bth:BT0553 0. glutamate synthase, large subunit K00265; Psort location: Cytoplasmic, score: 8.96.
      
 0.481
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
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