STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFB34254.1ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: pgi:PG0368 1.7e-214 DNA topoisomerase IV, B subunit, putative K02622; Psort location: Cytoplasmic, score: 8.96. (669 aa)    
Predicted Functional Partners:
EFB34825.1
DNA gyrase/topoisomerase IV, A subunit; KEGG: bth:BT3579 0. topoisomerase IV subunit A K01864.
 
 
 0.924
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
 
 0.883
EFB34253.1
Hypothetical protein; KEGG: gbe:GbCGDNIH1_0235 1.8e-17 dATP pyrophosphohydrolase K01529; Psort location: Cytoplasmic, score: 8.96.
     
 0.661
EFB36788.1
Transposase, IS4 family; Psort location: Cytoplasmic, score: 8.96.
   
   0.617
EFB36030.1
Transposase, IS4 family; Psort location: Cytoplasmic, score: 8.96.
   
   0.617
EFB35105.1
Transposase, IS4 family; Psort location: Cytoplasmic, score: 8.96.
   
   0.617
EFB35301.1
Transposase, IS4 family.
   
   0.617
EFB34721.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
   
   0.617
EFB34766.1
Hypothetical protein.
   
   0.617
EFB34769.1
Hypothetical protein.
   
   0.617
Your Current Organism:
Prevotella copri
NCBI taxonomy Id: 537011
Other names: P. copri DSM 18205, Prevotella copri CB7, Prevotella copri DSM 18205, Prevotella copri JCM 13464, Prevotella copri str. DSM 18205, Prevotella copri strain DSM 18205
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.