| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFB34186.1 | EFB34187.1 | PREVCOP_06354 | PREVCOP_06355 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Putative YigZ family protein; KEGG: spa:M6_Spy1374 2.8e-24 Xaa-Pro dipeptidase K01271; Psort location: Cytoplasmic, score: 8.96. | 0.824 |
| EFB34186.1 | pdxB-2 | PREVCOP_06354 | PREVCOP_06353 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 4-phosphoerythronate dehydrogenase; KEGG: bfs:BF2073 6.9e-117 serA; putative D-3-phosphoglycerate dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.26; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.694 |
| EFB34186.1 | serC | PREVCOP_06354 | PREVCOP_06352 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.623 |
| EFB34187.1 | EFB34186.1 | PREVCOP_06355 | PREVCOP_06354 | Putative YigZ family protein; KEGG: spa:M6_Spy1374 2.8e-24 Xaa-Pro dipeptidase K01271; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.824 |
| EFB34187.1 | pdxB-2 | PREVCOP_06355 | PREVCOP_06353 | Putative YigZ family protein; KEGG: spa:M6_Spy1374 2.8e-24 Xaa-Pro dipeptidase K01271; Psort location: Cytoplasmic, score: 8.96. | 4-phosphoerythronate dehydrogenase; KEGG: bfs:BF2073 6.9e-117 serA; putative D-3-phosphoglycerate dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.26; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.636 |
| EFB34187.1 | serC | PREVCOP_06355 | PREVCOP_06352 | Putative YigZ family protein; KEGG: spa:M6_Spy1374 2.8e-24 Xaa-Pro dipeptidase K01271; Psort location: Cytoplasmic, score: 8.96. | Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.623 |
| EFB34810.1 | glyA | PREVCOP_05790 | PREVCOP_04258 | Hypothetical protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.711 |
| EFB34810.1 | pdxB-2 | PREVCOP_05790 | PREVCOP_06353 | Hypothetical protein. | 4-phosphoerythronate dehydrogenase; KEGG: bfs:BF2073 6.9e-117 serA; putative D-3-phosphoglycerate dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.26; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.429 |
| EFB34810.1 | serC | PREVCOP_05790 | PREVCOP_06352 | Hypothetical protein. | Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.738 |
| EFB34810.1 | thrC | PREVCOP_05790 | PREVCOP_06056 | Hypothetical protein. | Threonine synthase; KEGG: bfs:BF0560 2.3e-180 thrC; threonine synthase K01733; Psort location: Cytoplasmic, score: 8.96. | 0.428 |
| EFB35749.1 | EFB35751.1 | PREVCOP_04653 | PREVCOP_04655 | KEGG: bth:BT3936 1.1e-93 prephenate dehydratase K04518; Psort location: Cytoplasmic, score: 9.97. | Putative 3-deoxy-7-phosphoheptulonate synthase; KEGG: bfs:BF3717 1.6e-142 putative chorismate mutase K04516:K03856; Psort location: Cytoplasmic, score: 8.96. | 0.995 |
| EFB35749.1 | serC | PREVCOP_04653 | PREVCOP_06352 | KEGG: bth:BT3936 1.1e-93 prephenate dehydratase K04518; Psort location: Cytoplasmic, score: 9.97. | Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.620 |
| EFB35749.1 | thrC | PREVCOP_04653 | PREVCOP_06056 | KEGG: bth:BT3936 1.1e-93 prephenate dehydratase K04518; Psort location: Cytoplasmic, score: 9.97. | Threonine synthase; KEGG: bfs:BF0560 2.3e-180 thrC; threonine synthase K01733; Psort location: Cytoplasmic, score: 8.96. | 0.462 |
| EFB35751.1 | EFB35749.1 | PREVCOP_04655 | PREVCOP_04653 | Putative 3-deoxy-7-phosphoheptulonate synthase; KEGG: bfs:BF3717 1.6e-142 putative chorismate mutase K04516:K03856; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT3936 1.1e-93 prephenate dehydratase K04518; Psort location: Cytoplasmic, score: 9.97. | 0.995 |
| EFB35751.1 | cysK | PREVCOP_04655 | PREVCOP_06742 | Putative 3-deoxy-7-phosphoheptulonate synthase; KEGG: bfs:BF3717 1.6e-142 putative chorismate mutase K04516:K03856; Psort location: Cytoplasmic, score: 8.96. | Cysteine synthase A; KEGG: bth:BT3080 2.2e-120 cysteine synthase A K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.422 |
| EFB35751.1 | serC | PREVCOP_04655 | PREVCOP_06352 | Putative 3-deoxy-7-phosphoheptulonate synthase; KEGG: bfs:BF3717 1.6e-142 putative chorismate mutase K04516:K03856; Psort location: Cytoplasmic, score: 8.96. | Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.625 |
| cysK | EFB35751.1 | PREVCOP_06742 | PREVCOP_04655 | Cysteine synthase A; KEGG: bth:BT3080 2.2e-120 cysteine synthase A K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Putative 3-deoxy-7-phosphoheptulonate synthase; KEGG: bfs:BF3717 1.6e-142 putative chorismate mutase K04516:K03856; Psort location: Cytoplasmic, score: 8.96. | 0.422 |
| cysK | glyA | PREVCOP_06742 | PREVCOP_04258 | Cysteine synthase A; KEGG: bth:BT3080 2.2e-120 cysteine synthase A K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.590 |
| cysK | pdxB-2 | PREVCOP_06742 | PREVCOP_06353 | Cysteine synthase A; KEGG: bth:BT3080 2.2e-120 cysteine synthase A K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 4-phosphoerythronate dehydrogenase; KEGG: bfs:BF2073 6.9e-117 serA; putative D-3-phosphoglycerate dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.26; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.631 |
| cysK | serC | PREVCOP_06742 | PREVCOP_06352 | Cysteine synthase A; KEGG: bth:BT3080 2.2e-120 cysteine synthase A K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.909 |