close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEG32296.1KEGG: tte:TTE1965 9.1e-35 birA; biotin-(acetyl-CoA carboxylase) ligase K03524:K01947; Psort location: Cytoplasmic, score: 8.87. (256 aa)    
Predicted Functional Partners:
hydE
Iron-only hydrogenase maturation rSAM protein HydE; KEGG: ctc:CTC01327 2.8e-81 biotin synthetase K01012; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.905
accB
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 
 0.879
EEG29646.1
Carboxyl transferase domain protein; KEGG: pab:PAB1769 1.5e-82 mmdA; methylmalonyl-CoA decarboxylase alpha chain K01604.
 
 
 0.859
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
 
 
0.852
EEG29645.1
Biotin-requiring enzyme; KEGG: tko:TK1624 1.2e-23 methylmalonyl-CoA decarboxylase, gamma subunit K01606.
 
  
 0.829
accC
acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
  
 0.827
EEG32295.1
KEGG: spd:SPD_1659 5.8e-17 phosphodiesterase, MJ0936 family protein; Psort location: Cytoplasmic, score: 8.87.
       0.819
tadA
Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
    0.818
yeaZ
Universal bacterial protein YeaZ; KEGG: ctc:CTC02444 7.4e-33 O-sialoglycoprotein endopeptidase K01409.
   
    0.787
EEG29367.1
Transcriptional regulator, AsnC family; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.785
Your Current Organism:
Clostridium methylpentosum
NCBI taxonomy Id: 537013
Other names: Clostridium methylpentosum ATCC 43829, Clostridium methylpentosum DSM 5476, Clostridium methylpentosum R2, [. methylpentosum DSM 5476, [Clostridium] methylpentosum DSM 5476
Server load: low (28%) [HD]