| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEG30141.1 | EEG30142.1 | CLOSTMETH_02239 | CLOSTMETH_02240 | AP endonuclease, family 2; KEGG: bte:BTH_II2059 5.0e-06 4-hydroxyphenylpyruvate dioxygenase, putative K00457. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | 0.459 |
| EEG30141.1 | nrdR | CLOSTMETH_02239 | CLOSTMETH_02241 | AP endonuclease, family 2; KEGG: bte:BTH_II2059 5.0e-06 4-hydroxyphenylpyruvate dioxygenase, putative K00457. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.430 |
| EEG30142.1 | EEG30141.1 | CLOSTMETH_02240 | CLOSTMETH_02239 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | AP endonuclease, family 2; KEGG: bte:BTH_II2059 5.0e-06 4-hydroxyphenylpyruvate dioxygenase, putative K00457. | 0.459 |
| EEG30142.1 | nrdR | CLOSTMETH_02240 | CLOSTMETH_02241 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.605 |
| EEG32296.1 | birA | CLOSTMETH_00034 | CLOSTMETH_02226 | KEGG: tte:TTE1965 9.1e-35 birA; biotin-(acetyl-CoA carboxylase) ligase K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.851 |
| EEG32296.1 | nadD | CLOSTMETH_00034 | CLOSTMETH_03192 | KEGG: tte:TTE1965 9.1e-35 birA; biotin-(acetyl-CoA carboxylase) ligase K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.653 |
| EEG32296.1 | nadE | CLOSTMETH_00034 | CLOSTMETH_03679 | KEGG: tte:TTE1965 9.1e-35 birA; biotin-(acetyl-CoA carboxylase) ligase K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.747 |
| EEG32296.1 | nrdR | CLOSTMETH_00034 | CLOSTMETH_02241 | KEGG: tte:TTE1965 9.1e-35 birA; biotin-(acetyl-CoA carboxylase) ligase K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.453 |
| birA | EEG32296.1 | CLOSTMETH_02226 | CLOSTMETH_00034 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | KEGG: tte:TTE1965 9.1e-35 birA; biotin-(acetyl-CoA carboxylase) ligase K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | 0.851 |
| birA | nadD | CLOSTMETH_02226 | CLOSTMETH_03192 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.653 |
| birA | nadE | CLOSTMETH_02226 | CLOSTMETH_03679 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.747 |
| birA | nrdR | CLOSTMETH_02226 | CLOSTMETH_02241 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.453 |
| nadD | EEG32296.1 | CLOSTMETH_03192 | CLOSTMETH_00034 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | KEGG: tte:TTE1965 9.1e-35 birA; biotin-(acetyl-CoA carboxylase) ligase K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | 0.653 |
| nadD | birA | CLOSTMETH_03192 | CLOSTMETH_02226 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.653 |
| nadD | nadE | CLOSTMETH_03192 | CLOSTMETH_03679 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.966 |
| nadD | nrdR | CLOSTMETH_03192 | CLOSTMETH_02241 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.448 |
| nadE | EEG32296.1 | CLOSTMETH_03679 | CLOSTMETH_00034 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | KEGG: tte:TTE1965 9.1e-35 birA; biotin-(acetyl-CoA carboxylase) ligase K03524:K01947; Psort location: Cytoplasmic, score: 8.87. | 0.747 |
| nadE | birA | CLOSTMETH_03679 | CLOSTMETH_02226 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.747 |
| nadE | nadD | CLOSTMETH_03679 | CLOSTMETH_03192 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.966 |
| nadE | nrdR | CLOSTMETH_03679 | CLOSTMETH_02241 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.483 |