close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hydEIron-only hydrogenase maturation rSAM protein HydE; KEGG: ctc:CTC01327 2.8e-81 biotin synthetase K01012; Psort location: Cytoplasmic, score: 8.87. (341 aa)    
Predicted Functional Partners:
hydF
Hydrogenase maturation GTPase HydF; KEGG: hpa:HPAG1_1378 1.0e-13 putative thiophene/furan oxidation protein K00058; Psort location: Cytoplasmic, score: 8.87.
   
 0.983
EEG29526.1
Putative iron-only hydrogenase system regulator; KEGG: lmo:lmo2076 0.0061 similar to ribosomal protein alanine acetyltransferase K03789; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.955
EEG32296.1
KEGG: tte:TTE1965 9.1e-35 birA; biotin-(acetyl-CoA carboxylase) ligase K03524:K01947; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.905
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.905
EEG32321.1
Hydrogenase, Fe-only; KEGG: tte:TTE0894 4.8e-109 nuoG; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) K00336; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.878
hydG
Iron-only hydrogenase maturation rSAM protein HydG; KEGG: chy:CHY_2448 1.3e-18 biotin synthase K01012; Psort location: Cytoplasmic, score: 8.87.
 
   
0.859
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
    
 0.791
LYS1
KEGG: spd:SPD_0812 1.7e-161 lys1; saccharopine dehydrogenase K00290; Psort location: Cytoplasmic, score: 8.87.
   
 
  0.771
EEG32304.1
4Fe-4S binding domain protein; KEGG: ctc:CTC02417 2.5e-112 periplasmic [Fe] hydrogenase 1 K00533; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.708
EEG29522.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.654
Your Current Organism:
Clostridium methylpentosum
NCBI taxonomy Id: 537013
Other names: Clostridium methylpentosum ATCC 43829, Clostridium methylpentosum DSM 5476, Clostridium methylpentosum R2, [. methylpentosum DSM 5476, [Clostridium] methylpentosum DSM 5476
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.