| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEG28528.1 | EEG30801.1 | CLOSTMETH_03914 | CLOSTMETH_01556 | DNA-binding helix-turn-helix protein. | KEGG: cjr:CJE1336 9.2e-58 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 8.87. | 0.424 |
| EEG28528.1 | EEG30803.1 | CLOSTMETH_03914 | CLOSTMETH_01558 | DNA-binding helix-turn-helix protein. | KEGG: ctc:CTC01806 9.6e-230 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.87. | 0.868 |
| EEG28528.1 | metK | CLOSTMETH_03914 | CLOSTMETH_03175 | DNA-binding helix-turn-helix protein. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.758 |
| EEG30575.1 | metK | CLOSTMETH_01788 | CLOSTMETH_03175 | NAD dependent epimerase/dehydratase family protein; KEGG: vfi:VF0192 1.4e-84 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; Psort location: Cytoplasmic, score: 8.87. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.965 |
| EEG30801.1 | EEG28528.1 | CLOSTMETH_01556 | CLOSTMETH_03914 | KEGG: cjr:CJE1336 9.2e-58 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 8.87. | DNA-binding helix-turn-helix protein. | 0.424 |
| EEG30801.1 | EEG30803.1 | CLOSTMETH_01556 | CLOSTMETH_01558 | KEGG: cjr:CJE1336 9.2e-58 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 8.87. | KEGG: ctc:CTC01806 9.6e-230 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.87. | 0.999 |
| EEG30801.1 | metK | CLOSTMETH_01556 | CLOSTMETH_03175 | KEGG: cjr:CJE1336 9.2e-58 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 8.87. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.849 |
| EEG30803.1 | EEG28528.1 | CLOSTMETH_01558 | CLOSTMETH_03914 | KEGG: ctc:CTC01806 9.6e-230 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.87. | DNA-binding helix-turn-helix protein. | 0.868 |
| EEG30803.1 | EEG30801.1 | CLOSTMETH_01558 | CLOSTMETH_01556 | KEGG: ctc:CTC01806 9.6e-230 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.87. | KEGG: cjr:CJE1336 9.2e-58 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 8.87. | 0.999 |
| EEG30803.1 | EEG32090.1 | CLOSTMETH_01558 | CLOSTMETH_00241 | KEGG: ctc:CTC01806 9.6e-230 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.87. | KEGG: det:DET0739 3.5e-81 aminotransferase, classes I and II K00821; Psort location: Cytoplasmic, score: 8.87. | 0.792 |
| EEG30803.1 | metK | CLOSTMETH_01558 | CLOSTMETH_03175 | KEGG: ctc:CTC01806 9.6e-230 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.87. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.914 |
| EEG30803.1 | speD | CLOSTMETH_01558 | CLOSTMETH_02410 | KEGG: ctc:CTC01806 9.6e-230 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.87. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.411 |
| EEG32090.1 | EEG30803.1 | CLOSTMETH_00241 | CLOSTMETH_01558 | KEGG: det:DET0739 3.5e-81 aminotransferase, classes I and II K00821; Psort location: Cytoplasmic, score: 8.87. | KEGG: ctc:CTC01806 9.6e-230 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; Psort location: Cytoplasmic, score: 8.87. | 0.792 |
| EEG32090.1 | metK | CLOSTMETH_00241 | CLOSTMETH_03175 | KEGG: det:DET0739 3.5e-81 aminotransferase, classes I and II K00821; Psort location: Cytoplasmic, score: 8.87. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.800 |
| dcm | dcm-2 | CLOSTMETH_01323 | CLOSTMETH_03581 | KEGG: spa:M6_Spy1143 9.9e-109 DNA-cytosine methyltransferase K00558; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | DNA (cytosine-5-)-methyltransferase; KEGG: hin:HI1041 7.4e-88 probable modification methylase HI1041 K00558; Psort location: Cytoplasmic, score: 8.87. | 0.885 |
| dcm | metK | CLOSTMETH_01323 | CLOSTMETH_03175 | KEGG: spa:M6_Spy1143 9.9e-109 DNA-cytosine methyltransferase K00558; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.781 |
| dcm | speD | CLOSTMETH_01323 | CLOSTMETH_02410 | KEGG: spa:M6_Spy1143 9.9e-109 DNA-cytosine methyltransferase K00558; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.756 |
| dcm-2 | dcm | CLOSTMETH_03581 | CLOSTMETH_01323 | DNA (cytosine-5-)-methyltransferase; KEGG: hin:HI1041 7.4e-88 probable modification methylase HI1041 K00558; Psort location: Cytoplasmic, score: 8.87. | KEGG: spa:M6_Spy1143 9.9e-109 DNA-cytosine methyltransferase K00558; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.885 |
| dcm-2 | metK | CLOSTMETH_03581 | CLOSTMETH_03175 | DNA (cytosine-5-)-methyltransferase; KEGG: hin:HI1041 7.4e-88 probable modification methylase HI1041 K00558; Psort location: Cytoplasmic, score: 8.87. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.765 |
| dcm-2 | speD | CLOSTMETH_03581 | CLOSTMETH_02410 | DNA (cytosine-5-)-methyltransferase; KEGG: hin:HI1041 7.4e-88 probable modification methylase HI1041 K00558; Psort location: Cytoplasmic, score: 8.87. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.756 |
