STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEG28982.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (179 aa)    
Predicted Functional Partners:
cobB
Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
       0.773
EEG28980.1
Hypothetical protein; KEGG: pha:PSHAb0209 0.0083 putative carbohydrate kinase K00924.
       0.768
topB
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
       0.751
EEG28983.1
Hypothetical protein.
       0.714
EEG28984.1
YhgE/Pip domain protein; KEGG: hhe:HH1686 0.0012 pycB; oxaloacetate decarboxylase K01570; Psort location: CytoplasmicMembrane, score: 9.99.
       0.520
EEG28978.1
Hypothetical protein.
       0.486
EEG28977.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.440
Your Current Organism:
Clostridium methylpentosum
NCBI taxonomy Id: 537013
Other names: Clostridium methylpentosum ATCC 43829, Clostridium methylpentosum DSM 5476, Clostridium methylpentosum R2, [. methylpentosum DSM 5476, [Clostridium] methylpentosum DSM 5476
Server load: low (22%) [HD]