node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACT57375.1 | acnA | CLIBASIA_04005 | CLIBASIA_01680 | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.990 |
ACT57375.1 | argH | CLIBASIA_04005 | CLIBASIA_01275 | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | COG0165 Argininosuccinate lyase. | 0.820 |
ACT57375.1 | attA | CLIBASIA_04005 | CLIBASIA_02445 | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 0.890 |
ACT57375.1 | gltA | CLIBASIA_04005 | CLIBASIA_01200 | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.983 |
ACT57375.1 | kgd | CLIBASIA_04005 | CLIBASIA_04765 | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.981 |
ACT57375.1 | mdh | CLIBASIA_04005 | CLIBASIA_04750 | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.935 |
ACT57375.1 | purB | CLIBASIA_04005 | CLIBASIA_04375 | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.812 |
ACT57375.1 | sdhB | CLIBASIA_04005 | CLIBASIA_04730 | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.852 |
ACT57375.1 | sucC | CLIBASIA_04005 | CLIBASIA_04755 | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.903 |
ACT57375.1 | sucD | CLIBASIA_04005 | CLIBASIA_04760 | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.846 |
acnA | ACT57375.1 | CLIBASIA_01680 | CLIBASIA_04005 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.990 |
acnA | argH | CLIBASIA_01680 | CLIBASIA_01275 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | COG0165 Argininosuccinate lyase. | 0.452 |
acnA | gltA | CLIBASIA_01680 | CLIBASIA_01200 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.996 |
acnA | kgd | CLIBASIA_01680 | CLIBASIA_04765 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.671 |
acnA | mdh | CLIBASIA_01680 | CLIBASIA_04750 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.630 |
acnA | sdhB | CLIBASIA_01680 | CLIBASIA_04730 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.875 |
acnA | sucC | CLIBASIA_01680 | CLIBASIA_04755 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.524 |
acnA | sucD | CLIBASIA_01680 | CLIBASIA_04760 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.605 |
argH | ACT57375.1 | CLIBASIA_01275 | CLIBASIA_04005 | COG0165 Argininosuccinate lyase. | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.820 |
argH | acnA | CLIBASIA_01275 | CLIBASIA_01680 | COG0165 Argininosuccinate lyase. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.452 |