STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (258 aa)    
Predicted Functional Partners:
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 0.999
obg
GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
  
  
 0.858
putA
Proline/pyrroline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
   
 0.813
fmt
methionyl-tRNA formyltransferase [Helicobacter pylori J99].
       0.759
birA
Biotin--protein ligase [Wolinella succinogenes DSM 1740].
       0.759
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.740
rpmA
50S ribosomal protein L27 [Wolinella succinogenes DSM 1740]; Belongs to the bacterial ribosomal protein bL27 family.
     
 0.728
HCAN_0866
PARA FAMILY PROTEIN [Wolinella succinogenes DSM 1740].
       0.719
HCAN_0867
Putative regulator containing a COG1475 Spo0J predicted transcriptional regulator domain; Belongs to the ParB family.
       0.719
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
     
 0.717
Your Current Organism:
Helicobacter canadensis
NCBI taxonomy Id: 537970
Other names: H. canadensis MIT 98-5491, Helicobacter canadensis ATCC 700968, Helicobacter canadensis H438, Helicobacter canadensis MIT 98-5491, Helicobacter canadensis NCTC 13241, Helicobacter canadensis NLEP-16143, Helicobacter canadensis str. MIT 98-5491, Helicobacter canadensis strain MIT 98-5491
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